Loading...
Journal of Oral Science Research

Archive

    28 September 2019, Volume 35 Issue 9 Previous Issue    Next Issue
    For Selected: Toggle Thumbnails
    Research Progress of Risk Factors of Immediate Loading Dental Implant Restorations in Edentulous Patients
    WANG Zhiying, LI Ruipiao
    2019, 35(9): 821-826.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.001
    Abstract ( 523 )   PDF (1032KB) ( 284 )  
    With the improvement of dental implant restoration technique and people’ living level, as well as the enhancement of people's awareness of oral health care, more and more patients with dentition defects and loss take implant repair as the first choice. All-on-4 or All-on-X immediate loading technique of edentulous patients not only greatly shortens the period of tooth loss, but also reduces the number of operations and saves time and cost, thus improving the quality of life of patients. The principle of All-on-4 is to use four implants in the mouth of patients with edentulous jaws to support a temporary, fixed, and immediately weight-bearing prosthesis. Many scholars at home and abroad have made clinical follow-up for patients with All-on-4 immediately loading, and obtained positive clinical effects, but there are also certain failure rates and postoperative complications. In this paper, the possible causes and postoperative complications of failure in All-on-4 immediate weight-bearing prosthesis are analyzed, with aim to provide reference for basic level dentists who will develop All-on-4 or All-on-X immediate loading restorations for edentulous patients.
    References | Related Articles | Metrics
    Biological Characteristics of Nanobacteria and the Relationship between Nanobacteria and Oral Stone Diseases
    WANG Songqing, ZHANG Zhimin
    2019, 35(9): 827-829.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.002
    Abstract ( 393 )   PDF (747KB) ( 372 )  
    Nanobacteria are atoms with special calcification capacity, which are found relevantly to many kinds of stone diseases in recent years. This article begins with the biological characteristics of nanobacteria, according to the present research progress,makes an overview of the relationship between nanobacteria and stone diseases. It aimed at providing reference for further research of nanobacteria in the oral cavity.
    References | Related Articles | Metrics
    An Update of Low-level Laser Therapy Applied for Bone Regeneration of Jaws
    XUE Guoping, LIU Qingmei
    2019, 35(9): 830-832.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.003
    Abstract ( 319 )   PDF (766KB) ( 330 )  
    Low-level laser therapy (LLLT) is a photobiomodulation therapy, which has a photobiomodulation effect on a variety of cells and can promote the healing of bone tissue. LLLT has gradually attracted the attention of clinicians. This paper reviewed the application of low-level laser (LLL) in vivo, in vitro, and in clinical research. Finally, the prospect of LLLT research is proposed, and it provides a reference for the future clinical application of LLLT in the field of oral.
    References | Related Articles | Metrics
    Application of 3D Printing Technology in Clinical Diagnosis and Treatment of Orthodontics
    HUA Chaochao, ZHANG Ronghe
    2019, 35(9): 833-836.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.004
    Abstract ( 464 )   PDF (821KB) ( 688 )  
    After its inception, 3D printing technology has played an important role in various fields. 3D printing technology is acclaimed as the subversive technology and has changed the traditional manufacturing industry. The technology has a close relationship with dental medicine. With the development of three-dimensional imaging technology and advancement in modeling techniques, such as cone-beam computed tomography, model scanning and intra-oral scanning technology, and CAD/CAM technology in the dental field, the progress and improvement of 3D printing technology are promoted. Under the background of digital medicine and precise medical model, 3D printing technology has become more and more widely used in the clinical diagnosis and treatment of orthodontics, and has provided tremendous support for clinical diagnosis and treatment. This article reviews the application of 3D printing technology in the clinical diagnosis and treatment of orthodontics.
    References | Related Articles | Metrics
    The State of Art of Decompression in Management of Radicular Cysts
    HUANG Zijing, HU Xiaoli
    2019, 35(9): 837-840.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.005
    Abstract ( 404 )   PDF (778KB) ( 701 )  
    Radicular cysts are the common jaw cyst and are often treated by root canal treatment. For large radicular cysts, enucleation is necessary. Although enucleation can achieve satisfactory therapeutic effects, it increases the risks of damaging other vital structures and the roots of adjacent teeth. As an adjuvant treatment of large odontogenic cysts, marsupialization/decompression is less invasive and causes less complication, which has drawn attention from endodontists and had been successfully applied in recent years. Its mechanisms may include the release of intracysic pressure and enhancement of osteogenesis, drainage, and reduction of the IL-1 which mediates osteoclast formation, which therefore changes the microenvironment reducing division of epithelial cells. Decompression also facilitates drainage of the cystic exudate so that the root canal can be completely dried and sealed. The present paper aimed to review the developments of decompression as a supplementary procedure in the management of radicular cysts and conclude that decompression might be adopted as part of a comprehensive strategy for treatments of radicular cysts.
    References | Related Articles | Metrics
    A Modified Surgical Technique with Novel Suspensory Suture for Periodontal Accelerated Osteogenic Orthodontics: Design, Application, and Preliminary Evaluation
    YANG Dong, HUA Xianming, LI Hanyue, DONG Weili, ZHANG Chen, CAO Zhengguo
    2019, 35(9): 841-845.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.006
    Abstract ( 258 )   PDF (5507KB) ( 704 )  
    Objective: To improve periodontal accelerated osteogenic orthodontics (PAOO) technique and suspensory suture method, and to preliminarily evaluate the effects of them. Methods: The PAOO technique and suspensory suture method were modified respectively. Six patients were treated with new operative and suture methods. 2 mm partial thickness flap was dissected from 3 or 4 mm below gingival margin. Full-thickness flap was preformed downwards. In the operation area, bone dust and gingival flap were restored. The needle and thread were passed through flap, and then were passed from the bottom of gingival papilla to the lingual gingival sulcus. The needle was placed around the lingual surface of the tooth, and was passed from the bottom of gingival papilla on the other side of the tooth, and then passed through the flap. The procedure was repeated and the suture was brought back to the starting point. Cone-beam computed tomography (CBCT) were used to evaluate the alveolar bone before and 3 months after surgery. Graphpad was used to carry out statistic analyze. Results: CBCT showed the thickness of buccal alveolar in root-middle 1/3 of the anterior tooth root increased from (0.98±0.33) mm to (3.64±0.89) mm, and the thickness of root-apical 1/3 increased from (1.28±0.57) mm to (3.97±1.04) mm. The bone thickness of root-middle and -apical significantly increased. Conclusion: The novel PAOO method with modified suspensory suture can effectively increase the bone thickness of buccal alveolar. The modified methods showed effective clinical results. However, long term follow-up is still needed in further study.
    References | Related Articles | Metrics
    Analysis of Tooth Loss and Alveolar Bone Loss in the Treatment of Patients with Generalized Aggressive Periodontitis
    CHEN Jie, XIA Fengjun, WANG Hui
    2019, 35(9): 846-849.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.007
    Abstract ( 227 )   PDF (766KB) ( 248 )  
    Objective: To investigate the changes of tooth loss and alveolar bone in the treatment of patients with generalized aggressive periodontitis (GAgP) as well as its potential risk factors. Methods: The clinical data of 36 patients with GAgP who were admitted in our hospital between March 2017 and March 2018 were retrospectively analyzed. 472 teeth were treated with basic treatment. The clinic attachment loss (CAL), depth of probing (PD), bleeding index (CI), alveolar crest gray value (HU), and alveolar crest height (%) were detected and measured by cone beam CT(CBCT) before and 3 months after treatment to determine the incidence of shedding and risk factors. The correlation of shedding risk factors was evaluated by linear regression models. Results: The BI, CAL, and PD before and after treatment in all patients were significant improved (P<0.05). The total alveolar crest height in 3 months after treatment was significantly higher than that before treatment (P<0.05). The difference of alveolar HU value was statistically significant compared with that before treatment (P<0.05). According to the single factor linear regression analysis, smoking was the main cause of tooth loss in GAgP patients. Conclusion: Patients with GAgP can be effectively improved in tooth loss and alveolar bone loss after treatment.
    References | Related Articles | Metrics
    Analysis of Clinical Epidemiological Data of 9942 Patients in Department of Periodontology
    CAI Yilin, MENG Ziyan, WANG Chun, LIU Linhua, DONG Weili
    2019, 35(9): 850-853.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.008
    Abstract ( 235 )   PDF (843KB) ( 268 )  
    Objective: To provide a clinical evidence for the prevention and treatment of periodontal diseases. Methods: Clinical data of 9942 patients examined by the same physician from January 2016 to December 2018 in the Department of Periodontology, School and Hospital of Stomatology, Wuhan University were collected. Age and gender distribution of patients and the reasons for treatment were analyzed. Results: The ratio of male to female patients was 1:1.05. Most of the patients were between 25 and 54 years old. The top three reasons for treatment were gingival bleeding (24.95%), teeth loosing (22.46%), and gingival swelling/pain (16.37%). Out of 9942 patients, 80.53% were diagnosed as chronic periodontitis. The referral rate from other departments and hospitals was 15.34%. Conclusion:Patients diagnosed as chronic periodontitis account for the majority of outpatients and most of them were between 25 to 54 years old. The rate of return visits was more than one in three and nearly one-sixth of patients were referred to the Department of Periodontology. Carrying out specific periodontal treatment was the needs of both patient's condition and other departments.
    References | Related Articles | Metrics
    Inflammatory Gene Expression in Chronic Periodontitis and Peri-implantitis in Patients with Type 2 Diabetes
    WU Peng, GAO Chengzhi
    2019, 35(9): 854-857.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.009
    Abstract ( 226 )   PDF (767KB) ( 270 )  
    Objective: To investigate the effects of metabolic changes on inflammatory factors and monocyte chemotactic in patients with type 2 diabetes mellitus (DM), as well as to study their gene expression levels in chronic periodontitis (CP) and peri-implantitis (P-IM). Methods: 143 patients with periodontal disease and 24 healthy individuals (control group) in our hospital from June 2016 to December 2018 were selected. The disease exposure factors were compared. The clinical indicators of different types of patients were compared. The mRNA expression levels of inflammatory factors such as tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and interleukin-8 (IL-8) in the periodontal and implants were detected. The correlation of inflammatory factors among different patients was determined. Results: The age, high fasting blood glucose, high glycosylated hemoglobin (HbA1c) level, and smoking history were risk factors for CP and P-IM diseases. The percentage of plaque index (PLI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), attachment loss (AL), and bone loss (BL) in patients with periodontal disease were higher than those in control group. GI, PD, AL, and BL in patients with poor blood sugar control were significantly higher than those in patients with good blood sugar control. Among patients with DM, the expression of TNF-α was more obvious in patients with P-IM, and the expression of IL-6 and IL-8 was more obvious in patients with CP. TNF-α, IL-6, and IL-8 were highly expressed in patients with poor blood sugar control. TNF-α, IL-6, and IL-8 were positively correlated with the severity of CP and P-IM diseases among patients with poor blood sugar control (P<0.05). Conclusion: Among DM free patients, inflammatory response in P-IM is more serious than that in CP, while DM can aggravate the progression of CP and P-IM diseases by affecting the expression of inflammatory factors in vivo.In addition, the hyperglycemia status in DM patients has a greater impact on GI, PD, AL, and BL.
    References | Related Articles | Metrics
    Effect of Premolars Extraction on Upper Airway Morphology in ClassⅠHyperdivergent Patients
    QIAO Xing, ZHANG Shilong, KANG Wenjing, LIU Chunyan, HU Xiaoying, LU Haiyan
    2019, 35(9): 858-862.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.010
    Abstract ( 207 )   PDF (996KB) ( 141 )  
    Objective: To evaluate the morphology changes in the upper airway after premolars extraction in patients with ClassⅠhyperdivergent. Methods: 26 patients were selected,whose cervical morphology showed that growth was finished. 4 boys and 9 girls were included in the non-extraction group [average age: (17.62±3.45) years], 3 boys and 10 girls were included in the extraction group [average age:(16.85±3.51)years]. The hard tissues and upper airway were measured by the cephalometrics before and after treatment. The data were analyzed with statistical software. Results: After treatment, U1-NA(mm) and L1-NB(mm) increased significantly in the non-extraction group (P<0.05). The U1-SN(°), U1-NA (mm), U1-NA(°), L1-MP(°), L1-NB(mm), L1-NB(°), and MP-FH(°) decreased significantly in the extraction group (P<0.05). There were no significant differences in both groups for hard tissues, upper airway, tongue, and hyoid between pretreatment and posttreatment (P>0.05). ΔU1-SN(°), ΔU1-NA (mm), ΔU1-NA (°), ΔL1-MP(°), ΔL1-NB (mm), ΔL1-NB(°) changed significantly(P<0.05). There was no significant difference between the non-extraction and extraction groups in the changes of hard tissues, upper airway, tongue, and hyoid (P>0.05). Conclusion: The effects of premolars extractionon in upper airway morphology in patients with ClassⅠhyperdivergent was limited.
    References | Related Articles | Metrics
    Effect of Cyclic-tension Strain on mRNA Levels of Leukemia Inhibitory Factor and Leukemia Inhibitory Factor Receptor in Human Periodontal Ligament Cells
    LIANG Youde, WEI Wei, XUE Weiwei, ZHOU Ruiping, FU Runying, WANG Yining
    2019, 35(9): 863-867.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.011
    Abstract ( 187 )   PDF (2635KB) ( 185 )  
    Objective: To investigate the effects of cyclic-tension strain on the expression of LIF and LIFR in human periodontal ligament cells (HPDLC), and to illustrate the molecular mechanism underlying orthodontic periodontal tissue remodeling. Methods: In this study, HPDLC were subjected to 18% elongation by strain unit at 0.1Hz for 48h and 72h. The expressions of LIF, LIFR, and ALP mRNA were measured by real-time quantitative RT-PCR. Morphological changes were observed after mechanical stress. Results: Cells inclined parallel to each other and aligned their long axis perpendicular to the stretching force vector. The status was more and more transparent with extension of time. qRT-PCR showed that mRNA expression of LIF, LIFR, and ALP changed upon the stimulation. The expressions of LIF and LIFR were increased dramatically (P<0.01) and the expression of ALP was decreased significantly (P<0.01) after 72h. Conclusion: LIF and LIFR may play an role in periodontal tissue remodeling induced by orthodontic therapy.
    References | Related Articles | Metrics
    Relationship between Caries Status and Oral Health Behaviors among Children Aged 3-5 Years in Guangxi, China
    ZHOU Kaiyan, LIU Qiulin, CHEN Bolin, WU Minqiong, YU Xueting, WU Shanshan, CHEN Shaoyong, CHEN Wenxia, ZENG Xiaojuan
    2019, 35(9): 868-871.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.012
    Abstract ( 219 )   PDF (763KB) ( 197 )  
    Objective: To investigate the caries status and explore the relationship between oral health behaviors and the prevalence of caries in children aged 3~5 years in Guangxi, China. Methods: A total of 1949 children aged 3-5 years were selected from kindergartens in Guangxi by using multi-stage stratified equal-volume random sampling method for oral health examination, and face-to--face questionnaire survey was conducted among parents. Logistic regression was used to explore the relationship between oral health behaviors and caries. Results: The prevalence of caries in children aged 3-5 years in Guangxi was 72.3%, and the mean dmft was 4.52. After adjusting for age, gender, parental education and place of residence, higher frequency of sweet snacks, sweet drinks and taking sweets before going to bed were significantly associated with higher risk of caries. After adjusting for oral health behaviors, urban children still have a higher probability of caries than rural. Conclusion: Children aged 3-5 years in Guangxi have serious caries. The frequency of sweet snacks, sweet drink intake, and the frequency of eating sweets before going to bed are related to children's caries. Oral health behaviors cannot fully explain the differences in caries between urban and rural children.
    References | Related Articles | Metrics
    Effect of Chronic Apical Periodontitis on Plasma Cytokine and Aorta Intima in Rats
    MA Dianfu, CHEN Shuai, XIAO Suli, LI Pingping, HUANG Xiaojing
    2019, 35(9): 872-875.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.013
    Abstract ( 188 )   PDF (2253KB) ( 236 )  
    Objective: To investigate the effect of chronic apical periodontitis (CAP) for 12 weeks on rat plasma cytokines response and lesion of aorta. Methods: 32 male SD rats were randomly divided into high fat diet group and normal diet group. After 9 weeks, according to the teeth number of opening pulp cavity, the rats were divided into four groups (n=8) to build CAP model, namely N0, N6, H0 and H6. After 24 weeks, plasma concentrations of lipid (TC, TG, HDL-C, LDL-C) and inflammation cytokine (CRP, IL-2, IL-6, IL-10) were detected. Histological examinations of aorta were performed by HE staining and sudan Ⅳ staining. Results: There were no significant difference in plasma CRP, IL-2, IL-6 and IL-10 among four groups (P>0.05). Aorta intima was smooth without obvious inflammation cell adhesion in N0 group. A small amount of inflammatory cells were found in muscularis and adventitia among N6, H0 and H6 groups. Conclusion: CAP for 12 weeks on rats did not raise plasma concentration of cytokine, neither did it when combined with hyperlipidemia. CAP infection caused slight inflammatory cells infiltration in rat aorta.
    References | Related Articles | Metrics
    Research on Clinical Effect of M3 Nickel-titanium (NiTi) for Primary Teeth in Root Canal Therapy in Children
    LIU Qiong, REN Fei, QIAN Hong, FANG Jingxian, LIU Hedi, WU Xiaoming
    2019, 35(9): 876-878.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.014
    Abstract ( 270 )   PDF (741KB) ( 292 )  
    Objective: To study the clinical effect of M3 nickel-titanium ( NiTi) for primary teeth in root canal therapy in children. Methods: 80 teeth with chronic pulpitis in 80 patients aged 3-8 years were divided into two groups by case-control design: M3 rotary nickel-titanium group and stainless steel K files group with 40 cases in each group. The operation time, postoperative pain degree, and postoperative X-ray were recorded, respectively. Results: There was no difference in postoperative X-ray evaluation and the pain degree in day 7 between two groups(P>0.05). The differences of the operation time and the pain degree at day 1 and day 3 were statistically significant (P<0.05). The experimental group needed shorter operation time and the level of pain at day 1 and day 3 was lower. Conclusion: M3 nickel-titanium (NiTi) for primary teeth should be promoted because it can shorten the root canal treatment time and reduce the degree of postoperative pain of patients.
    References | Related Articles | Metrics
    A Comparative Study on Fracture Resistance of Difference Prosthesis Design of Mandibular Premolar Teeth after Root Canal Therapy
    JIA Ying, WANG Pin, WANG Zhenguo, LIU Min
    2019, 35(9): 879-882.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.015
    Abstract ( 227 )   PDF (1984KB) ( 324 )  
    Objective: To compare the fracture strength and fracture mode of crown, onlay, and occlusal veneer made by IPS e.max Press for mandibular premolar teeth after root canal treatment. Methods: The mandibular premolars treated with root canal were randomly divided into 4 groups with 6 detached teeth in each group, resin filling in group A was used as the control group, crown restoration in group B, onlay in group C, and occlusal veneer in group D. Four groups of specimens were statically loaded until the specimen was damaged. The damage value and fracture mode were recorded. SPSS 20.0 software was used for statistical analysis of the experimental. Results: The fracture strength of four groups of samples were (1136.50±338.34), (1947.83±411.60), (2335.00±747.45), and (2249.50±632.38) N. The differences between three experimental groups and the control group were all significant (P<0.05). There was no significant difference between the experimental groups. Conclusion: The fracture strength of experimental groups was significantly higher than that of control group. There was no significant difference in flexural strength between the experimental groups.
    References | Related Articles | Metrics
    Diagnostic Values of Salivary MicroRNA-375 for OSCC and Its Effects on Biological Function of OSCC Cells
    XIE Long, SANG Lei, SONG Zhuoying, JIANG Yanjun
    2019, 35(9): 883-888.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.016
    Abstract ( 213 )   PDF (3047KB) ( 223 )  
    Objective: To explore the diagnostic value of salivary miR-375 for patients with oral squamous cell carcinomas (OSCC) and investigate the potential effects of miR-375 on biological characteristics of OSCC cells. Methods: Saliva samples from 20 OSCC patients and 20 healthy controls were collected. RT-PCR was applied to compare the relative expression of miR-375. SCC-4 cells were cultured and transfected with miR-375 mimics (miR-375 mimic group) via Lipofectamine 2000 liposome. HN-6 cells were cultured and transfected with miR-375 inhibitor (miR-375 inhibitor group) via Lipofectamine 2000 liposome. All cells without transfection were used as control group. The cell proliferation and cell apoptosis were measured by EDU and flow cytometry. The migration and invasion ability of the cells were detected by scratch test and Transwell test, respectively. Results: The expression of salivary miR-375 in OSCC patients was significantly lower than that in healthy control group (P<0.05). The low expression of miR-375 in SCC-4 cells, after miR-375 mimicking transfection, inhibited the cell proliferation, promoted the apoptosis, and decreased the cell migration and invasive ability. The highly expression of miR-375 in HN-6 cells, after miR-375 inhibitor transfection, promoted the cell proliferation, inhibited the apoptosis,and increased the cell migration and invasive ability. Conclusion: Our study indicates that miR-375 is down expression in the saliva of patients with OSCC and likes a tumor suppressor gene in OSCC, and it could be used as an indicator of diagnosis of OSCC in future.
    References | Related Articles | Metrics
    Imaging Features Analysis of Odontogenic Sclerosing Carcinoma and Literature Review
    Pakezhati Seyiti, ZHANG Lei, WANG Tiemei, HUANG Xiaofeng, LIN Zitong, SUN Guowen
    2019, 35(9): 889-893.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.017
    Abstract ( 215 )   PDF (5495KB) ( 225 )  
    Objective: To investigate the clinical and imaging features of sclerosing odontogenic carcinoma (SOC) and discuss its differential diagnosis after reviewing the literatures. Methods: The radiological and pathological appearances of a case diagnosed pathologically as SOC in our hospital were retrospected and summarized. After reviewing the literatures, its imaging diagnosis and differential diagnosis were discussed. Results: In our case, the lesion occupied the right mandible body to the left mandible ascending branch area, and showed irregular cavity-shaped radiolucency with an unclear border mixed with a patchy high density of ossifies. Obvious thickening was present on mandible body, the buccal and lingual cortex were absorbed, and osteogenesis of periosteum was also exists. According to literature review, the imaging classifications were proposed as localized type, diffuse type, and soft tissue mass type. Conclusion: As an extremely rare disease, the imaging manifestations of odontogenic sclerosing carcinoma are complex and diverse, but lack of characteristics. More case reports are quite essential to precisely diagnose this disease.
    References | Related Articles | Metrics
    Effects of Tanshinol on RANKL/OPG of Alveolar Osteoblasts
    ZHANG Xiaoyan, LIU Yunxin, WU Tie
    2019, 35(9): 894-897.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.018
    Abstract ( 183 )   PDF (809KB) ( 195 )  
    Objective: To investigate the effects of tanshinol on the RANKL/OPG expression of alveolar osteoblasts. Methods: Alveolar osteoblasts of SD rats were cultured by primary cell culture. The alveolar osteoblasts of the fourth generation were treated with different concentrations (0.01, 0.10, 0.50, 1.00, 5.00 mg/L) of tanshinol serum. The proliferation rate of osteoblasts and the mRNA and protein expression levels of OGP and RANKL were detected by MTT, RT-PCR, and western blotting after the use of different concentrations of tanshinol serum on 1 d, 3 d, and 5 d, respectively. Results: The effect of tanshinol on the proliferation of alveolar osteoblasts varied with concentration and time of drugs. The proliferation rate was the highest when the alveolar osteoblasts were treated with 5 mg/L tanshinol at day 3. Compared with the control group, OGP mRNA and protein expression increased (P<0.05). Conclusion: Tanshinol could promote the proliferation of alveolar osteoblasts by increasing the expression of OGP mRNA and protein.
    References | Related Articles | Metrics
    In Vitro Drug Release of Dental Flow Resin Modified by Core-shell Shaped CHX/ACP Nanospheres
    XU Zexian, YANG Yanwei, QIU Yinong, LI Zhiqiang, WANG Xuefeng, WANG Rui, ZHENG Xin, LIU Bin
    2019, 35(9): 898-901.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.019
    Abstract ( 185 )   PDF (1427KB) ( 282 )  
    Objective: To investigate the in vitro drug release of dental flow resin (FiltekTM Z350XT Flow Resin) modified by chlorhexidine/amorphous calcium phosphate (CHX/ACP) nanospheres with core-shell structure. Methods: The core-shell CHX/ACP nanospheres was synthesized and characterized. Nanospheres were added to FiltekTM Z350XT flow resin in different mass percentages (1%, 5%, and 10%) as experimental group, but unmodified flow resin as control group. The sample leaching solutions were prepared and the releases of calcium, phosphorus, and CHX at different time points were measured. Results: Three groups of experimental resins continuously released calcium, phosphorus, and CHX in deionized water. The release amounts all significantly increased with the increase of the added proportion of nanospheres, and also increased with the prolongation of soaking time. The release rate decreased with time. The release of the control group was approximately zero and did not change with time. Conclusion: Flow resin with different proportions of core-shell CHX/ACP can continuously release calcium,phosphorus, and CHX slowly. The addition proportion of nanoparticles has a significant effect on drug release.
    References | Related Articles | Metrics
    Study on Three Dimensional Digitized Dental Model Based on Intraoral Scanners and Cone-beam Computed Tomography
    ZOU Chen, ZOU Daoxing, AI Yilong
    2019, 35(9): 902-905.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.020
    Abstract ( 588 )   PDF (3416KB) ( 620 )  
    Objective: To establish digitized dental model with root based on three-dimensional intraoral scanning and CBCT data, and to record the digital information of crown, root, and occlusion. Methods: Upper and lower dentitions of a female volunteer were scanned by CBCT and intraoral scanner. The resulting DICOM data was used for 3D reconstruction in Mimics software, and the independent digital teeth models with roots data were established. A dentition model with teeth roots was regrouped with independent teeth models built from CT data, and the intraoral dentition model data in Geomagic wrap software. Results: Upper and lower 3D digital full structure dentition models were rebuilt containing details of the morphology and position of the crowns and roots of teeth, and the occlusal relationship of upper and lower dentitions. Conclusion: Three-dimensional intraoral scanning combined with CBCT was used to establish a digital model of full dentition including tooth root. It could realize the observation, measurement, and analysis of the changes in the anatomical morphology, position or displacement of the crown, and the tooth root intuitively in orthodontic treatment.
    References | Related Articles | Metrics
    Clinical Study on Application of Digital Impression in Full Arch Fixed Implant Restoration
    JIANG Bo, ZHANG Xuezhou, XIANG Mei, ZHOU Fengxin, LI Nan, ZHANG Lei, ZHENG Huiyuan
    2019, 35(9): 906-909.  DOI: 10.13701/j.cnki.kqyxyj.2019.09.021
    Abstract ( 253 )   PDF (2972KB) ( 310 )  
    Objective: To investigate the clinical effect of digital impression in the restoration of fixed denture with full arch implantation. Methods: We obtained the digital impression in patients with complete dental arch implantation who had completed the first stage operation, then designed and fabricated temporary and permanent restoration structure to complete the restoration of fixed denture. At the same time, patients were asked to fill the visual analogue scale according to their comfort level to the digital impression. The clinical effect of digital impression was evaluated according to the position and marginal suitability of the prostheses, patient compfort level and postoperative follow-up. Results: All temporary and final fixed dentures were placed precisely in passive position at one time, and the fitness of prosthesis reached I degree. The comfort scores of immediate denture and permanent dentures were 84.2±2.4 and 90.5±3.9, respectively. The abutment screws of the implant were not loosened or broken, and the alveolar bone absorption was within 2mm. Conclusion: Digital impression has high accuracy, patient comfort level, and good clinical prognosis in the restoration of full arch fixed implant denture.
    References | Related Articles | Metrics