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28 March 2022, Volume 38 Issue 3 Previous Issue    Next Issue

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Application of Metabolomics in the Early Diagnosis and Precise Treatment of Oral Squamous Cell Carcinoma HU Qingang, NI Yanhong, WANG Yuhan 2022, 38(3): 207-211.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.001 Abstract ( 389 )   PDF (1039KB) ( 370 )   Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors of the head and neck. Currently the 5-year survival rate of the patients is only about 60%. Difficulties for early diagnosis and precise treatment are important factors for its poor prognosis. One of the reasons is the lack of relevant tumor biomarkers for early screening and precise diagnosis. Researches have shown that, similar to other malignant tumors, OSCC also undergone significant metabolic reprogramming. Therefore, for altered obtaining changed metabolic enzymes and metabolites by metabolomics may be helpful for early screening and precise diagnosis of OSCC. This review shows the findings of metabolomics related to OSCC in recent years and hope to present new ideas or methods for improving the early diagnosis and precise therapy of OSCC patients,and advancing their survival rate. References | Related Articles | Metrics

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Research Progress of Three-dimensional Graphene and Its Derivatives in Osteogenesis of Dental Stem Cells YE Qing, LI Jiyao 2022, 38(3): 212-215.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.002 Abstract ( 208 )   PDF (820KB) ( 312 )   Graphene is a novel material with broad applications in many fields. Its research in biomedical field is increasing in recent years. Three-dimensional graphene refers to the two-dimensional graphene assembly with three-dimensional structure. The three-dimensional structure shows better porosity and larger surface area of graphene, which improves the adhesion and growth of cells, making it capable of inducing bone formation of mesenchymal stem cells. Based on the physical and chemical properties and biocompatibility of three-dimensional graphene, this review summarizes the researches on three-dimensional graphene and its derivatives in inducing osteogenesis of dental stem cells, with hope to provide reference for the osteogenesis application of graphene in dental research. References | Related Articles | Metrics

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Research Progress of Gingipain of Porphyromonas Gingivalis WANG Dan, MENG Weiyan 2022, 38(3): 216-219.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.003 Abstract ( 496 )   PDF (826KB) ( 757 )   Periodontitis is a chronic inflammatory disease of tooth-supporting tissues. It could give a rise to a progressive loss of attachment by destructing the connective tissue and alveolar bone, and may eventually lead to tooth loss. Gram-negative anaerobic bacterium Porphyromonas gingivalis (P. gingivalis) is an important pathogen of chronic periodontitis, which expresses several virulence factors, including lipopolysaccharide, fimbriae, hemagglutinins, and cysteine proteinases. Among them, gingipains (belonging to cysteine proteinases) account for most (85%) of the general proteolytic activity caused by P. gingivalis, and have been considered as the essential virulence factor. This review discusses the gingipains's classification, secretion, pathogenic effects, and inhibitors. References | Related Articles | Metrics

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Research Progress of MicroRNA in Osteogenic Differentiation of Periodontal Ligament Stem Cells ZHAO Jun, LIU Lina 2022, 38(3): 220-222.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.004 Abstract ( 254 )   PDF (801KB) ( 386 )   Periodontitis is a common chronic infectious disease, which can lead to the progressive destruction of periodontal supporting tissues. Periodontal ligament stem cells have the ability of osteogenic differentiation, which have broad application prospects in the field of periodontal tissue regeneration. MicroRNA (miRNA) is a non-coding single stranded RNA with a length of 18-25 nucleotides. It can target the 3 'untranslated region (UTR) of mRNA, resulting in degradation of mRNA or inhibition of mRNA translation. In recent years, many scholars have studied the osteogenic regulation of miRNA, and a variety of miRNA have been confirmed to be involved in the osteogenic regulation of periodontal ligament stem cells. In this paper, the current research progress of miRNA in regulating the osteogenic differentiation of periodontal ligament is reviewed. References | Related Articles | Metrics

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Research Progress of the Cracked Teeth Syndrome FAN Jian, XU Qingan 2022, 38(3): 223-225.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.005 Abstract ( 321 )   PDF (773KB) ( 524 )   Cracked teeth syndrome is a common tooth hard tissue injury, often combined with pulp and/or periodontal symptoms. The diagnosis and treatment of cracked teeth are difficult and complex, and the prognosis is uncertain. This article makes a comprehensive review on the symptoms, classification, etiology, diagnosis, treatment, and prognosis of cracked teeth. References | Related Articles | Metrics

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Retrospective Study of Vascular Stapler Used for Free Tissue Flap to Repair Tongue Defect WANG Meiyue, MI Hongyan, LIU Mengzhe, LIU Yiming, SUN Jingjing, LI Rui 2022, 38(3): 226-229.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.006 Abstract ( 154 )   PDF (1526KB) ( 168 )   Objective: To retrospectively analyze the effect of vascular stapler in repairing tongue defects with free tissue flaps. Methods: Eighty-eight cases of free skin flap transplantation to repair tongue defect from January 2020 to December 2020 in the First Affiliated Hospital of Zhengzhou University were selected. The patient's clinical information, anastomosis, and skin flap transplantation complications were recorded. The Health Impact Scale (OHIP-14) was used to assess the oral health-related quality of life (OHRQOL) of patients 6 months after surgery. Results: In 88 cases, 51 cases (57.95%) were anastomosed with a stapler for the artery and vein of the skin valve, and 37 cases (42.05%) were anastomosed with a stapler only for the vein and 42.05% for the artery. The use of a stapler shortened the vascular anastomosis time. The survival rate of skin flap transplantation was 100%. The items with better recovery of OHIP-14 score were social disorder and disability, and the worse were physical pain and psychological discomfort. Conclusion: The use of vascular stapler for free tissue flaps to repair tongue defects is effective and can improve patients' OHRQOL. References | Related Articles | Metrics

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Effect of Tooth Extraction on Fistula Formation in Tongue Cancer Patients Who Underwent Radical Surgery FAN Tengfei, ZHANG Sheng, WU Hanjiang, WU Kun 2022, 38(3): 230-233.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.007 Abstract ( 175 )   PDF (1421KB) ( 240 )   Objective: To evaluate the effect of tooth extraction on fistula formation in tongue cancer patients who underwent radical surgery. Methods: The patients with tongue cancer who underwent radical surgery using an anterolateral thigh flap were recruited from January 2017 to January 2020 in the Department of Oral and Maxillofacial Surgery at the Second Xiangya Hospital. The participants were divided into 2 groups, based on whether the extraction of mandibular anterior teeth was performed with disconnecting mandible. Results: A total of 243 patients with tongue cancer were recruited, of whom 222 were male and 21 were female. The mean age of these patients was (50.38±10.21) years (rang 26 to 71). Although the incidence of experimental group(5.7%)was higher than that of control group(1.5%), no significant differences were found(P>0.05). In the Logistic regression model for the occurrence of fistula, the No. of veins anastomosis(P=0.0061), flap compromise (P<0.0001), and tooth extraction(P=0.0049) were found to be associated with fistula. Conclusion: The reserve of tooth in tongue cancer patients who underwent radical surgery with disconnecting mandible could prevent the occurrence of fistula. References | Related Articles | Metrics

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Effect of Nose Pad Adjustment on Correction of Nostril Shape During the Application Process of Computer-assisted Preoperative Appliance for Unilateral Complete Cleft Lip and Palate YAN Yixuan, CHEN Yuxiang, HUANG Qun 2022, 38(3): 234-237.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.008 Abstract ( 175 )   PDF (2310KB) ( 191 )   Objective: To observe the effect of using computer-assisted simulation to adjust the position of nose pad on improving the shape of nasal columella during the treatment of infants with unilateral complete cleft lip and palate before the operation. Methods: Twenty-five children with unilateral complete cleft lip and cleft palate were selected as the experimental group. The inclination angle of the nasal columella, the height and width of the nostril, and alveolar cleft before and after treatment were measured. Twenty-five patients whose parents refused to undergo preoperative correction were selected as the control group. The inclination of the nasal columella, the height and width of the nostrils, and the alveolar fissure were measured at 1-6 weeks and 3 months. Results: In the experimental group, the height of the nostril increased significantly, and the inclination of the nasal columella, the width of the nostril, and the alveolar fissure were significantly reduced (P<0.05). In the control group, there was no significant change in the inclination of the nasal columella and the height of the nostrils in the children who did not undergo nasal alveolar shaping before cleft lip and palate surgery (P>0.05). However, the width of the nostril and the fissure of the alveolar process were still significantly increased (P<0.05). Conclusion: The computer-aided design guides the adjustment of the nose pad of the orthodontic appliance before the operation, which has a good effect on the correction of the nostril shape effect of the children with unilateral complete cleft lip and palate, which is helpful to reduce the difficulty of the operation. References | Related Articles | Metrics

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Study on the Correlation between Soft Palate and Velopharyngeal Closure after Incomplete Cleft Palate Surgery FENG Xiaowei, LI Xiangjun, LIU Xiaolin, DOU Chenlei, ZHANG Xiao, FENG Ying, ZHANG Xiaoyan, DI Lu 2022, 38(3): 238-242.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.009 Abstract ( 158 )   PDF (1742KB) ( 215 )   Objective: To investigate the relationship between soft palate and velopharyngeal closure function after incomplete cleft palate surgery through the application of lateral head X-ray in the evaluation of velopharyngeal closure function after incomplete cleft palate surgery. Methods: Forty patients with incomplete cleft palate surgery (VPC 15 cases, MVPI 10 cases, VPI 15 cases) from January 2017 to December 2019 who had undergone one-stage cleft palate surgery for more than half a year were selected as the research object, 10 normal cases were set as control group. Their head lateral X-rays were collected and analyzed. Results: The overall distribution of PU, PW, the need ratio, BC/BD, and ∠B2PC2 in the normal group, VPC group, MVPI group, and VPI group were statistically different (P<0.05). And the following cut-off point, i.e. PW≥23.50 mm, the need ratio≥0.81, PU≤23.50 mm, sagittal soft palate closure degree≤0.858, and ∠B2PC2≤29°, could be considered as significance of clinical diagnosis. Conclusion: The velopharyngeal closure function after cleft palate surgery is closely related to the length and mobility of the soft palate. Postoperative lateral head X-ray examination can be used to evaluate the patient's velopharyngeal closure function. References | Related Articles | Metrics

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A Prognostic Research of Adjacent Teeth with External Root Resorption Caused by Full Bony Impacted Wisdom Teeth WANG Kan, HE Zheng, ZHANG Lei 2022, 38(3): 243-247.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.010 Abstract ( 247 )   PDF (1226KB) ( 458 )   Objective: To investigate the effects of different treatments for full bony impacted wisdom teeth on the prognosis of adjacent second molar with external root resorption. Methods: 52 asymptomatic second molars were included with external root resorption caused by full bony impacted teeth, and then divided into two groups--test group (extraction of the impacted wisdom teeth) and control group (reservation of the impacted wisdom teeth)-according to the willing of fully informed patients. As long-term follow-up was taken, symptoms and signs were recorded and comparatively analyzed, including the progress of external root resorption, pulp vitality, distal probing depth (PD) of the second molar. Results: No continuous progress of external root resorption was observed in both the test group and the control group. Pulp symptoms were observed in 5 teeth in test group in which 2 teeth were proved transient sensitivity, 2 teeth with pulp necrosis were applied root canal therapy and 1 teeth were extracted finally. Pulp symptoms were not observed in other 27second molars. The postoperative distal PD of the second molars in the test group became deeper with significant difference; while in the control group, there was no significant difference in the distal PD before and after the follow-up. The difference of the changes of the distal PD between the two groups was statistically significant. Conclusion: Removal of the full bony impacted teeth might not be the only option for the compromised adjacent teeth with external root resorption. To the cases that the impacted wisdom must be extracted, the pulp of adjacent second molars should also be protected during operation. References | Related Articles | Metrics

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Primary Clinical Application of 3D Printing Complete Dentures LIU Yuxiao, LIN Feifei, YU Shujuan, HUANG Xiaoyan, ZHU Guoxiong 2022, 38(3): 248-251.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.011 Abstract ( 274 )   PDF (3200KB) ( 375 )   Objective: To primary explore the application of 3D scanning and 3D printing technique in the restoration of edentulous patient. Methods: 30 edentulous cases (Atwood class 1-4) visited our hospital from 3/1/2018 to 5/1/2020 were selected. The cases were randomly divided into 2 groups: the traditional complete denture group (Group A) and the 3D printing complete denture group (Group B). Each group had 15 cases. Group A used traditional method to manufacture the complete denture, and Group B used 3D scanning, CAD (Computer-aided design), 3D printing, and duplicate denture technique to manufacture the dentures. The patients' satisfaction was measured using the visual analogue scale (VAS) at 4 time points: immediately after denture delivery, 1 month, 3 months, and 6 months following denture delivery. Results: The ability to speak and chew and the comfort of two groups of dentures were gradually improved in the first three time points. The VAS scores increased to a satisfy level after 3 months. The esthetics and stability of two groups of dentures scored high since the initial delivery. The VAS scores of two groups on esthetics, ability to speak, ability to chew, stability, and comfort had no statistic difference (P>0.05) on each time point. The visiting times of 3D printing complete denture were significantly decreased in comparison to traditional complete denture. Conclusion: 3D printing complete denture can restore the edentulous patients rapidly, so as to meet the patients’ demanding of esthetic and function. References | Related Articles | Metrics

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Deviation Analysis of Digital Model of Edentulous Jaw with Two Impression Methods YU Nian, CAO Yang, YU Qing 2022, 38(3): 252-255.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.012 Abstract ( 225 )   PDF (2333KB) ( 295 )   Objective: To explore the mucosal changes of maxillary edentulous jaw by using digital scanning technology and reverse engineering software, and to compare the differences of edentulous jaw models under different mold taking methods. Methods: Twenty patients with edentulous maxillary were randomly selected. The maxillary impression was obtained by two different methods. The traditional anatomical impression was obtained by using a perforated tray and alginate material, and the pressure impression was obtained by using a nonporous tray and silica material. Then, all impressions were scanned with an extraoral scanner (D810, 3shape) and converted into a digital model. A pair of models of the same patient was registered using the "best matching method". Results: The best fitting alignment method showed that there was significant difference in mucosal deviation between edentulous anatomical model and pressure model. The area with the smallest deviation was located in the alveolar ridge area, and the area with the largest deviation was the postdam area. Conclusion: The mucosal deformation of pressure impression was significantly higher than anatomical impression. There are differences in the deformation of the whole model, maxillary hard area, and postdam area. References | Related Articles | Metrics

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Effect of Scanning Method and Surface Characteristics of Model on Scanning Accuracy of Full Dentition GAO Maomao, GUO Xiaoyang, MA Xiaoping, LI Shaoping, CHEN Zhiyu 2022, 38(3): 256-260.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.013 Abstract ( 209 )   PDF (2198KB) ( 283 )   Objective: To assess the effect of surface characteristics of the model and the scanning method on the accuracy of direct intraoral scanning. Methods: The upper and lower dentition models made of plaster and resin were scanned 6 times with a laboratory scanner and an intraoral scanner to verify the precision of the scanner. Then, the digital model obtained by the laboratory scanner was taken as the reference model, and the intraoral scanning data using three different scanning methods was set as the registration model. Through the three-dimensional registration technology, the difference in both models was observed. Results: For precision of laboratory scanning, there was no statistical differences between the upper and lower dentition of the plaster model [(15.03±1.61) μm and (16.13±1.68) μm, P>0.05], while the resin model had statistical differences [(75.92±15.52) μm and (48.51±9.27) μm, P<0.05]. For precision of intraoral scanning, there was no statistical difference between three scanning methods for both plaster and resin models. For trueness of intraoral scanning, the sequential scanning method [(73.67±21.08) μm, (52.88±8.23)μm] was significantly higher than duplex scanning method and cross scanning method in plaster model (P<0.05), while there was no statistical difference among three scanning methods for resin model (P>0.05). The accuracy of the plaster model was generally greater than that of the resin model (P<0.05). Conclusion: The surface characteristics of the model and the scanning method will affect the accuracy of the scan data. Specific scanning procedures should be used for direct intraoral scanning of full dentition. References | Related Articles | Metrics

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Femtosecond Laser-induced Microstructure on Dental Zirconia Ceramics and Its Effect on Bonding Properties SONG Yiting, ZHU Li, XU Yidi, LIU Siwen, LIN Tingting, HUANG Shengbin, LIN Jixing, Ma Jianfeng 2022, 38(3): 261-267.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.014 Abstract ( 248 )   PDF (3327KB) ( 301 )   Objective: To study the influence of femtosecond laser processing on the topographies of yttria-stabilised tetragonal zirconia polycrystal (Y-TZP) and its bonding strength with self-adhesive resin cement. Methods: One hundred and twenty cases of sintered zirconia ceramic specimens were randomly divided into six research groups and treated as follows. Group A: Control group with no treatment; group B: alumina sandblasting; C-F group: surface femtosecond laser linear groove processing, processing repetitions were 2, 4, 6, and 10 times, respectively. Topographic surface analysis and groove depth were performed by laser confocal microscope (CLSM). Surface roughness Ra was measured by atomic force microscope (AFM). Crystal phase was evaluated by X-ray diffraction (XRD). Surface morphology was observed by scanning electron microscopy (SEM). The specimens were then subjected to shear bond strength testing of zirconia ceramic and self-adhesive resin cement before and after aging (5000 cycles with temperature range from (5±1) ℃ to (55±1) ℃ for 30s each). Further, stereomicroscope was used to observe the fracture modes. Results: In this study, regular V-shaped grooves with depths of about 30 μm, 50 μm, 60 μm, and 70 μm were obtained after 2, 4, 6, and 10 times of laser pulses scanning on the surface of zirconia. The surface roughness increased with the increase of laser scanning times. Laser surface treatment does not lead to surface crystal phase transformation. The microstructure showed that after laser ablation by laser, the zirconia ceramic substrate had no craters, holes, ridges, and other defects, but too many scanning times (10 times) could be seen in the casting layer accumulation. The V-shaped grooves on the ceramic surface increased the surface area and formed an interlocking structure with the resin. The shear strength increased from 3.68 MPa and 4.87 MPa in group A (control group) and group B (sandblasting group) to 17.78 MPa (group C), 22.5 MPa (group D), 27.4 MPa (group E), and 27.54 MPa (group F), and the shear strength after aging was still more than 5 times that of the control group. The fracture mode changed from complete bond failure of the control group and the sandblasting group to cohesive failure and mixed failure. The flexural strength of the zirconia ceramic after laser treatment was 457.73 MPa (group E), which met the requirements of clinical application. Conclusion: Femtosecond laser processing is one of the ideal methods for surface modification of dental ceramics. Reasonable microstructure design can significantly improve the bonding strength with self-adhesive resin cement, and has good anti-aging property. It can replace the traditional surface treatment methods such as sandblasting to prolong the service life of dentition defect repair. References | Related Articles | Metrics

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In Vivo Safety Evaluation of Flexible Ceramic Materials SUN Qian, FENG Lifang, LI Jingdong, WANG Wuliang, HAN Ziwen, LIANG Ruiying 2022, 38(3): 268-274.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.015 Abstract ( 158 )   PDF (13174KB) ( 138 )   Objective: To investigate the biosafety of flexible ceramic materials. Methods: The material extract or button samples were prepared. Skin irritation test, intradermal reaction test, delayed type hypersensitivity test, oral mucosal irritation test, and acute systemic toxicity test were conducted according to GB/T16886 biological evaluation series of medical devices. Results: The flexible ceramic material had no irritation, no intradermal reaction, no sensitization, no irritation of oral mucosa, and no short-term systemic toxicity. Conclusion: Flexible ceramic materials have excellent biosafety and meet the application requirements of oral surface contact materials. References | Related Articles | Metrics

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ARHGAP29 Regulates Proliferation of Mouse Embryonic Palatal Mesenchymal Cells RUAN Wenyan, HOU Yuzhuan, CHI Dandan, YU Lili, DUAN Xiaohong, HUANG Yongqing 2022, 38(3): 275-279.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.016 Abstract ( 228 )   PDF (2699KB) ( 270 )   Objective: To investigate the effect of ARHGAP29 on proliferation of cells from mouse embryonic palatal mesenchymal (EPM). Methods: Immunohistochemical technique was used to confirm the expression of ARHGAP29 in mice palate. The mice EPM cells of GD13.5-day were cultured in vitro. Immunofluorescence technique was used to identify the cellular characteristics. The primary cultured EPM cells were transfected with three pair of Arhgap29-siRNA to establish a gene knockdown cell model. The efficiency of gene knockdown was detected by real-time PCR and western blotting methods. The effects of Arhgap29 gene silencing on the proliferation of EMP cells were assessed by CCK-8 assay. Results: The results of immunohistochemistry showed that ARHGAP29 was significantly expressed in the palate of GD13.5 mice. Immunofluorescence detection showed the strong positive green fluorescence staining of Vimentin in cytoplasm and the negative staining of Cytokeratinc. Real-time PCR and western blotting results indicated that the mRNA and protein level of ARHGAP29 were significantly down-regulated in Arhgap29-siRNA group comparing with blank and negative control, and Arhgap29-siRNA3 showed the best silencing effect (P<0.001). The results of CCK8 assay showed that the proliferation ability of EPM cells began to increase after 48 hours Arhgap29-siRNA3 treatment, and the OD value was significantly increased after 72 hours (P<0.05). Conclusion: Our results indicated that Arhgap29 can promote the proliferation of cells from mouse EMP, which may increase the adhesion of palatal shelves and oral epithelium during the embryonic stage, and affect the palate normal development. References | Related Articles | Metrics

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CORM-3 Promotes Osteogenic Differentiation of MC3T3-E1 Cells by Regulating the Polarization of Macrophages WANG Yingying, DU Liuyi, LV Huixin, WANG Yuhui, REN Sicong, ZHOU Yanmin 2022, 38(3): 280-285.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.017 Abstract ( 263 )   PDF (4908KB) ( 451 )   Objective: To study the regulation of carbon monoxide releasing molecule-3 (CORM-3) on macrophage polarization, and to further explore the effects of CORM-3 mediated macrophage immune environment on proliferation and osteogenic differentiation of MC3T3-E1. Methods: RAW264.7 cells were cultured in vitro and the available CORM-3 concentration was screened. The expression of M1 and M2 related genes, such as iNOS, TGF-β, and IL-10, were detected by RT-qPCR. Immunofluorescence staining was used to detect the expression of Heme oxygenase-1 (HO-1) protein in each group. Flow cytometry was used to detect the proportion of M1 and M2 macrophages in each group after 24 hours. The supernatant after 24 hours was collected to prepare conditioned medium. CCK-8, alkaline phosphatase staining, alizarin red staining, and RT-qPCR were used to detect the proliferation and osteogenic activity of MC3T3-E1 cells. Results: RT-qPCR results showed that CORM-3 promoted the expression of TGF-β and IL-10, and decreased the expression of iNOS (P<0.05). Immunofluorescence results showed that CORM-3 increased the protein of HO-1 in RAW264.7 cells. In the environment where CORM-3 regulated macrophages, RT-qPCR results showed that CORM-3 increased the expression of OCN, Runx2, and Col-1 (P<0.05). The proliferation and osteogenic differentiation of MC3T3-E1 were enhanced. Conclusion: CORM-3 can increase the protein level of HO-1 by releasing CO, promote the polarization of macrophages RAW264.7 cells to the M2 phenotype, and enhance the osteogenic differentiation ability of MC3T3-E1 cells. References | Related Articles | Metrics

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Maxillary Odontogenic Keratocyst Adjacent to Descending Palatine Artery:A Case Report ZHENG Kaiyao, OUYANG Kexiong, PIAO Zhengguo, CHEN Hao 2022, 38(3): 286-287.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.018 Abstract ( 248 )   PDF (2346KB) ( 282 )   Odontogenic keratocyst (OKC), derived from the original tooth embryo or tooth plate residue, is originated in the third molar region and the mandible branch. Cysts occurring in the maxilla and adjacent to the wing and palate of the maxillary artery are relatively rare. This case reported a maxilla multiple recurrencent, multiple surgical, and tooth-derived keratinized cystic tumor adjacent to the palate descending artery. References | Related Articles | Metrics

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Severely Worn Dentition Treated with Whole Process Digitization Self-glazed Zirconia Occlusion Veneer Bridge:a Case Report LI Ruifeng, SU Zhikang, CHEN Ding, GUO Lvhua 2022, 38(3): 288-290.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.019 Abstract ( 296 )   PDF (1927KB) ( 458 )   Self-glazed zirconia is a new generation of digital three-dimensional colloidal forming all ceramic zirconia, whose performance is improved than the traditional zirconia. The whole process digitization self-glazed zirconia occlusal veneer can achieve ideal restoration effect under the condition of high efficiency and accuracy in the cost of a small amount of teeth preparation. This paper reports a case of severely worn dentition treated with whole process digitization self-glazed zirconia occlusion veneer bridge with good clinical effect. References | Related Articles | Metrics

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Decompression of the Left Mandibular Unicystic Ameloblastoma: A Case Report LI Tingting, WANG Chaofan, ZHAO Jihong 2022, 38(3): 291-294.  DOI: 10.13701/j.cnki.kqyxyj.2022.03.020 Abstract ( 219 )   PDF (8409KB) ( 325 )   Unicystic ameloblastoma generally occurs in young people, between 10 to 29 years old. The mandible is the most frequent site of unicystic ameloblastoma. The treatment often used is curettage. Conservative approaches are recommended as the treatment for younger patients. This article presented a case of unicystic ameloblastoma in the left mandible, which was treated by marsupialization combined with curettage. References | Related Articles | Metrics