Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (3): 218-220.DOI: 10.13701/j.cnki.kqyxyj.2019.03.005

Previous Articles     Next Articles

Research Progress of Dental Pulp Derived Stem Cells in Oral Craniofacial Tissue Engineering

HUANG Wen-yan, GE Li-hong*, ZENG Su-juan*   

  1. Key Laboratory of Oral Medicine, School and Hospital of Stomatology, Guangzhou Medical University, Guangzhou 510140, China.
  • Received:2018-05-03 Online:2019-03-28 Published:2019-04-01

Abstract: Recent evidences have shown that a variety of mesenchymal stem cells located in dental pulp-derived tissues such as the dental pulp and apical papilla. It is known that these stem cells have the potential to differentiate into several cell types, including odontoblasts, osteoblasts, and chondrocytes. These stem cells can be isolated and grown under defined tissue culture conditions, and are potential cells for use in tissue engineering, including dental tissues and bone regeneration. This article reviews the osteogenic properties of dental pulp stem cells, osteogenic system in vitro, and their applications in tissue engineering.

Key words: Dental pulp derived stem cells, Tissue engineering, Three-dimensional scaffold