Journal of Oral Science Research ›› 2020, Vol. 36 ›› Issue (2): 107-110.DOI: 10.13701/j.cnki.kqyxyj.2020.02.004

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Research Progress on Effects of Dental Follicle during Tooth Eruption and the Regulatory Mechanism

HE Mengting, BAI Ding*   

  1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-07-18 Online:2020-02-28 Published:2020-04-24

Abstract: Tooth eruption is a series of complicated physiological processes that the tooth moves through the alveolar bone and the oral mucosa until it finally reaches the functional position. The eruption process is strictly controlled in time and space. The dental follicle, a layer of loose connective tissue from ectomesenchyme surrounding the developing tooth germ, is necessary for tooth eruption. It plays a key role in the tooth eruption by recruiting monocytes and regulating bone resorption and formation. Hence, this review describes the recent research progress on the effects and regulatory mechanism of dental follicle during tooth eruption.

Key words: dental follicle, tooth eruption, osteoclasts, osteogenesis