Relationship between DNA Methylation and Recurrent Aphthous Ulcer

doi:10.13701/j.cnki.kqyxyj.2020.12.004

Abstract

Abstract: In recent years, it has been found that DNA methylation is closely related to the occurrence of oral diseases. As a common oral mucosal disease, recurrent aphthous ulcer has complex etiology. With the understanding of its pathogenesis, the changes of DNA methylation induced by its pathogenic factors have been paid more and more attention. In this paper, DNA methylation induced by the pathogenic factors of recurrent aphthous ulcer, such as microorganism, nutrition, and immunity, is reviewed, which plays an important role in the pathogenesis of the disease, providing new research ideas for clinical treatment in the future, and also contributing to the development and application of related therapeutic drugs.

Key words: DNA methylation, recurrent aphthous ulcer, microorganism, immune

ZHANG Wenjie, GUAN Cuiqiang. Relationship between DNA Methylation and Recurrent Aphthous Ulcer[J]. Journal of Oral Science Research, 2020, 36(12): 1095-1098.

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