Journal of Oral Science Research ›› 2015, Vol. 31 ›› Issue (10): 1047-1049.

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Research Progress of Freeze-drying and Combined Application of PRP and PRF

LIU Li-sha, ZHANG Bin, LI Yin   

  1. Department of Periodontology and Oral Mucosal Membrane, The Affiliated Second Hospital of Harbin Medical University. Harbin 150086, China
  • Received:2014-07-14 Online:2015-10-28 Published:2016-05-04

Abstract: Platelet concentrates for surgical use are innovative tools of regenerative medicine. Platelet-rich plasma (PRP) is the first generation of platelet concentrate that has been used widely to accelerate soft-tissue and hard-tissue healing. Platelet-rich fibrin (PRF), a new generation of platelet concentrates, is first described by Choukroun et al.It has been shown to have several advantages over traditional PRP. Freeze-drying is the conventional method to save biological products andis also an effective means to control scaffold pore size and preserve its composition. This article reviewed PRP, PRF, freeze-drying and the combined application in organization development and regeneration.

Key words: Platelet-rich plasma, Platelet-rich fibrin, Freeze-drying

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