Giant Pleomorphic Adenoma of Left Parotid Gland Malignant Transformation: A Case Report

doi:10.13701/j.cnki.kqyxyj.2024.07.016

Abstract

Abstract: The most common salivary gland tumor is pleomorphic adenoma, but particularly giant pleomorphic adenoma with malignant transformation is relatively rare. This article reports the diagnosis and treatment process of a 77-year-old male patient with malignant transformation of giant pleomorphic adenoma of left parotid gland. Physical examination showed a mass with a size of 20.0 cm×18.0 cm×18.0 cm, and the tumor was completely removed after surgery.

Key words: parotid gland, pleomorphic adenoma, giant, malignant transformation, surgery

LI Ke, LI Zihui, KOU Jiahao, SUN Guowen. Giant Pleomorphic Adenoma of Left Parotid Gland Malignant Transformation: A Case Report[J]. Journal of Oral Science Research, 2024, 40(7): 654-656.

References

[1] Gao M, Hao Y, Huang MX, et al. Salivary gland tumours in a northern Chinese population: a 50-year retrospective study of 7190 cases [J]. Int J Oral Maxillofac Surg, 2017, 46(3):343-349.
[2] 吕慧欣,王卓然,高愉淇,等.3724例唾液腺肿瘤的临床病理分析[J].中华口腔医学杂志,2019,54(1):10-16.
[3] Xu W, Zhang X, Wu Y, et al. Recurrent pleomorphic adenoma of the parotid gland: A population-based study with emphasis on re-recurrence and malignant transformation [J]. Head Neck, 2023, 45(3):697-705.
[4] Pei Y, Li W. Clinical parameters predictors of malignant transformation of recurrent parotid pleomorphic adenoma [J]. Sci Rep, 2023, 13(1):4543.
[5] AlKindi M, Ramalingam S, Hakeem LA, et al. Giant parotid pleomorphic adenoma with atypical histological presentation and long-term recurrence-free follow-up after surgery: A case report and review of the literature [J]. Case Rep Dent, 2020, 2020:8828775.
[6] Zoccali F, Cialente F, Colizza A, et al. Clinico-histopathological review of 255 patients who underwent parotidectomy for pleomorphic adenoma: a 10-year retrospective study-a proposal for an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma [J]. Eur Arch Otorhinolaryngol, 2023, 280(7):3329-3335.
[7] Committeri U, Arena A, Iaquino V, et al. Surgical management and side effects of parotid gland surgery for benign lesions: a retrospective analysis of our experience from 2012 to 2021 [J]. Br J Oral Maxillofac Surg, 2023, 61(6):411-415.
[8] Alzumaili B, Xu B, Saliba M, et al. Clinicopathologic characteristics and prognostic factors of primary and recurrent pleomorphic adenoma: A singleinstitution retrospective study of 705 cases [J]. Am J Surg Pathol, 2022, 46(6):854-862.
[9] Bonavolontà P, Dell'Aversana Orabona G, Maglitto F, et al. Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications [J]. Br J Oral Maxillofac Surg, 2019, 57(10):998-1002.

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