Research Progress of MicroRNAs in Field of Periodontics

doi:10.13701/j.cnki.kqyxyj.2017.09.026

Abstract

Abstract: MicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs that regulate gene expression. It plays a critical role in cell proliferation, cell differentiation, and organism development. Current researches on miRNAs mainly focus on its antitumor effect while its role in periodontics lacks attention. This review is focusing on the differential expression of miRNAs in periodontitis, osteoblast, and osteoclast differentiation, and discussing their possible regulation mechanism on the basis of the latest progress on researches of miRNAs in periodontitis.

Key words: MiRNA Periodontitis , Osteoblast differentiation, Osteoclast differentiation

CLC Number:

R781.4

XUE Nan, QI Lin, LIU Huan-ye, ZHANG Yang. Research Progress of MicroRNAs in Field of Periodontics[J]. Journal of Oral Science Research, 2017, 33(9): 1016-1018.

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