Journal of Oral Science Research ›› 2017, Vol. 33 ›› Issue (10): 1123-1126.DOI: 10.13701/j.cnki.kqyxyj.2017.10.026

• Orignal Article • Previous Articles     Next Articles

Research Progress on the Role of Macrophage during Biomaterials Induced Bone Information

LI Ming-Zheng1,2, XIAO Yu1, WU Zhen-zhen1, BAO Chong-Yun1,2*   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University. Chengdu 610041, China;
    2. Department of Oral and Maxillofacial Surgery, West China School of Stomatology, Sichuan University. Chengdu 610041, China.
  • Received:2016-09-01 Online:2017-10-20 Published:2017-10-24

Abstract: Objective: To review the research progress on the role of macrophage during osteoinduction. Methods: The literatures concerning this aspect were extensively reviewed and analyzed. Result: On one hand, macrophage has a key impact on bone formation. On the other hand, the surface topography and particle size of biomaterials can affect the function of macrophage in promoting bone formation. Conclusion: Understanding the role and mechanism of macrophage during osteoinction is important to accurate evaluate the osteoinduction of biomaterials. What's more, it is important to improve the property of biomaterials.

Key words: Macrophage, Osteoinduction , Bone formation, Biomaterials, Osteoblast

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