Effect of Semiconductor Laser on CGRP and 5-HT of Pulp Tissue during Whitening Procedure.

doi:10.13701/j.cnki.kqyxyj.2018.05.024

Abstract

Abstract: Objective: To observe the expression of calcitonin gene-related peptide(CGRP) and 5-hydroxytryptamine(5-HT) in rat molar pulp at different periods during the semiconductor laser whitening using continuous and interval frequencies. Methods: 3-month old male SD rats were randomly divided into group A, group B, and group C. Group B was continuous irradiation in 7 W, 20 Hz, and 15 s frequency for maxillary first and second molars of rats, which were sacrificed immediatelly (group B0), 1 d (group B1), 3 d (group B3), and 7 d (group B7). The irradiation in Group C was changed to 7 W, 20 Hz, and 30 s frequency at 1/2 interval. The expression of 5-HT and CGRP in the pulp tissue of rats maxillary first and second molars was measured by immunohistochemical method. Results: The expressions of CGRP and 5-HT in group B and group C were higher than that of group A. The immediate group began to rise, the 3 day group reached the highest, and then began to decrease. At the same time, group B was higher than group C. Conclusion: The stimulation of semiconductor laser whitening with continuous frequency was significantly higher than that with interval frequency. Laser irradiation immediately increased the expression of pain transmitters 3 days in the pulp, which should strengthen the protection of the pulp.

Key words: Semiconductor laser, Whitening procedure, Pulp, Calcitonin gene-related peptide 5-hydroxytryptamine

LI Chun-nian. Effect of Semiconductor Laser on CGRP and 5-HT of Pulp Tissue during Whitening Procedure.[J]. Journal of Oral Science Research, 2018, 34(5): 563-566.

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