Research Progress on the Role of Krüppel-like Factors 4 in Odontoblast Differentiation and Oral Squamous Cell Carcinoma

doi:10.13701/j.cnki.kqyxyj.2018.07.002

Abstract

Abstract: Krüppel-like factors 4 (KLF4), a member of the KLF family, is a zinc-finger transcription factor. KLF4 is involved in the regulation of proliferation, differentiation, apoptosis, somatic cell reprogramming, tumorigenesis, and many other important physiologic processes. The expression of KLF4 in the oral tissue is biochemically and functionally significant. This paper investigated the biochemical activities of KLF4, and the function of KLF4 in odontoblast differentiation and oral squamous cell carcinoma.

Key words: Krüppel-like factors 4, Odontoblast cells, Oral squamous cell carcinoma

HUANG Ling-yan, YE Sheng-jia, YE Yan-ling, FANG Ping-juan. Research Progress on the Role of Krüppel-like Factors 4 in Odontoblast Differentiation and Oral Squamous Cell Carcinoma[J]. Journal of Oral Science Research, 2018, 34(7): 692-694.

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