Evaluation of Antibacterial Ability of Epigallocatechin-3-gallate-modified Adhesive

doi:10.13701/j.cnki.kqyxyj.2021.02.009

Abstract

Abstract: Objective: To evaluate the antibacterial and bonding performance of adhesives incorporated with different concentrations of epigallocatechin-3-gallate (EGCG), and provide experimental support for the usage in preventing the occurrence of white spot lesions in orthodontic treatment. Methods: Four experimental groups were designed, namely 0 (Control group), 0.1, 1.0, and 10 g/L EGCG groups. The antibacterial ability of experimental adhesives was assessed by live/dead bacterial staining and MTT assay. The shear bond strength (SBS) and degree of conversion (DC) were evaluated to assess the bonding performance of experimental adhesives. Results: Comparing with the Control group, the incorporation of EGCG into adhesive significantly increased the antibacterial ability (P<0.05), which had positive correlation with EGCG concentration. No negative influence on the SBS and DC was detected for 0.1 and 1.0 g/L EGCG groups (P>0.05), but the value of 10 g/L EGCG group significantly decreased (P<0.05). Conclusion: The addition of 1.0 g/L EGCG into dental adhesive could exert positive antibacterial ability without hampering the polymerization of dental adhesive.

Key words: epigallocatechin-3-gallate, white spot lesion, adhesive, antibacterial

YANG Liuqing, Wang Bohao, XIE Lili. Evaluation of Antibacterial Ability of Epigallocatechin-3-gallate-modified Adhesive[J]. Journal of Oral Science Research, 2021, 37(2): 131-134.

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