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28 September 2022, Volume 38 Issue 9 Previous Issue    Next Issue

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Application of Bionic Concepts in Stomatology Research MA Jianfeng, WANG Cheng 2022, 38(9): 801-806.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.001 Abstract ( 240 )   PDF (989KB) ( 536 )   Biomimetic technology has become a hot topic for scholars at home and abroad, and is widely used in many popular industries and fields such as industrial manufacturing, construction engineering, and product modeling design. However, it is just emerged in the field of stomatology and in the initial stage of exploration and development. This review intends to start from some research hotspots in various disciplines in the field of stomatology, and summarizes the new ideas and strategies for stomatology researchers to explore and solve oral clinical problems by using the bionic inspiration and concepts given by various natural physiological phenomena. References | Related Articles | Metrics

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pplication of MicroRNAs in Diagnosis and Treatment of Oral Leukoplakia LIU Jiaxin, DAN Hongxia 2022, 38(9): 807-810.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.002 Abstract ( 190 )   PDF (847KB) ( 188 )   MicroRNA (miRNA) is an endogenous highly conserved non-coding RNA, which is involved in various biological activities of the body, and is closely related to the development of a variety of cancers. Recent studies have shown the potential of miRNAs as a molecular marker for malignant transformation of oral leukoplakia and therapeutic target of oral leukoplakia. In this study, the application of miRNAs in the diagnosis and treatment of oral leukoplakia was reviewed. References | Related Articles | Metrics

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Application of Virtual Simulation Technology in Dental Education. WANG Zhenhui, YANG Hongye 2022, 38(9): 811-814.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.003 Abstract ( 289 )   PDF (1449KB) ( 392 )   Virtual simulation technology is becoming an important part of modern education. Because of the advantages of intuition, operability, security, and unlimited time and space, virtual simulation is regarded as an advanced auxiliary means of dental education nowadays. In the preclinical education, it helps dental students improve their fine motor skills and hand-eye coordination, endows them theoretical knowledge and skills under a safe environment. At present, there have been many studies demonstrating the effectiveness of virtual simulation technology in dental education. This paper focuses on and summarizes the research progress and advantages of virtual simulation technology in dental education, and provides useful information for future dental education direction. References | Related Articles | Metrics

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Research Progress of NLRP3 in Radiation Injury of Oral and Maxillofacial Tissues WU Yuqi, HUANG Guilin 2022, 38(9): 815-818.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.004 Abstract ( 184 )   PDF (850KB) ( 247 )   Radiotherapy is one of the effective measures in the treatment of head and neck tumors. Radiotherapy often leads to tissue damage such as maxillofacial skin, jaw, oral mucosa, and so on, which limits its application to a certain extent and affects the prognosis of patients. Therefore, it is necessary to find an effective method to prevent and treat maxillofacial radiation injuries. At present, studies have proved that NLRP3 is closely related to radiation-induced diseases. Inhibiting the activation mechanism of NLRP3 may effectively alleviate tissue damage. This article reviews the structure and activation mechanism of NLRP3 inflammasome and its role in oral and maxillofacial tissue damage after radiation. References | Related Articles | Metrics

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Research Progress of Dental Protein-Repellent Resins PENG Song, ZHANG Wu 2022, 38(9): 819-822.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.005 Abstract ( 185 )   PDF (849KB) ( 306 )   Resin materials have been widely used in oral clinical treatment for their excellent aesthetic properties and bonding properties. However, their relatively rough and hydrophobic surface is easy to absorb salivary protein and form plaque, which may cause secondary caries, periodontitis, denture stomatitis, and other diseases. In recent years, the exploration of protein-repellent resins has become a hot spot in the field of oral materials research. In this paper, their anti-adsorption mechanism, material types, and application methods are reviewed. References | Related Articles | Metrics

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Study on Establishing Spatial Position of Multiple Implants by Scanning Model Combined with Reverse Engineering Technology. WU Yuwei, CAO Jia, HAN Fei, WEN Aonan, GAO Zixiang, LI Deli, TANG Zhihui, QIAN Jun, ZHAO Yijiao, WANG Yong 2022, 38(9): 823-826.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.006 Abstract ( 144 )   PDF (1469KB) ( 183 )   Objective: To establish spatial information of multi-implants in the cast model of edentulous patients, and to lay a foundation for comparing the spatial location of the same multi-implants obtained by different impression methods. Methods: The cast of the upper jaw with 6 implants was obtained by using a custom tray elastomeric impression procedure after splinting the impression copings at room temperature (23 ℃). The cast was scanned by a model scanner and a reference model database was outputted as the triangular grid data (stereolithography, STL). Results: In the Geomagic Control X software, the three dimension feature extraction of single and six abutment replica’s base plane, centerline, and center point under the same coordinate system were determined respectively. The discrepancy of spatial position of multiple implants between cast model and CBCT were conducted by feature extraction. Conclusion: The position and angle deviation of the single and six implant’s location are determined by the model scanner and Geomagic Control X software, and our study contributes to compare the spatial position of the same multi-implants obtained by different impression methods. References | Related Articles | Metrics

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Comparative Study on Accuracy of Dental Implants Guided by Dynamic Navigation in Different Areas. DUAN Linna, ZHANG Zhihong, LIU Honghong, HAN Qian, CHEN Jia, CHEN Yuyan. 2022, 38(9): 827-830.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.007 Abstract ( 169 )   PDF (880KB) ( 203 )   Objective: To analyze the influence of different areas on dynamic navigation by comparing the implant placement accuracy. Methods: According to the position of implant site, the patients were divided into four groups: anterior maxillary, posterior maxillary, anterior mandibular, and posterior mandibular. The implantation point deviation, angle deviation, and end point deviation of implants were analyzed. Results: Concerning the implant point deviation, there was significant difference in the anterior parts between upper and lower jaws (P<0.05). Concerning the angle deviation and end point deviation of implants, there were significant differences between anterior and posterior parts (P<0.05), and at the rear of the dental arch between upper and lower jaws (P<0.05). Conclusion: The accuracy of dynamic navigation-guided dental implantation varies according to the anatomical conditions and bone conditions of different parts of the jaw. References | Related Articles | Metrics

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Three-dimensional Finite Element Analysis of Impact of Implantation Site and Axial Direction on Fretting Degree with Immediate Implantation and Immediate Loading at Maxillary Central Incisor. DU Jun, QIU Yanju, WAN Zhe 2022, 38(9): 831-836.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.008 Abstract ( 116 )   PDF (1715KB) ( 157 )   Objective: To analyze and explore the influence of the implantation site and axial direction on the fretting degree of the implant when the maxillary central incisor is immediate implantated and immediate loaded with different typing based on the three-dimensional finite element method. Methods: The oral CBCT image data of a healthy adult were referred to establish the three-dimensional finite element model of the maxillary central incisor with three typing (partial lip, intermediate, and partial palate) of immediate implantation and immediate loading. Different implantation site (apical site and partial palatine/labial site) and axial direction (longitudinal axis of tooth and long axis of alveolar bone) were simulated. Stress with different angles (0°, 30°, 45°, 60°, 90°) were loaded. ANSYS software was used to analyze the displacement of the implant. Results: Twelve three-dimensional finite element models of the maxillary central incisor with different typing for immediate implantation and immediate loading were successfully established. For partial lip or partial palatine maxillary central incisor with immediate implantation and immediate loading, partial palate along the long axis of the tooth/lip site implantation was easier to obtain smaller fretting degree of the implant. When the intermediate maxillary central incisor is for immediate implantation and immediate loading, it is easier to obtain smaller fretting degree of the implant at the apical site along the long axis of the alveolar bone. Conclusion: Different typing, implantation site, and axial direction will affect the fretting degree of the immediate implantation and immediate loading of the maxillary central incisor. In clinical practice, different surgical plan should be formulated by different typing, implantation site, and axial direction. References | Related Articles | Metrics

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Accuracy of Recording Soft Tissue Contour by Different Impression Techniques after Interim Restoration of Single Implant in the Aesthetic Area. JIA Xiangbin, CAO Xiao, ZHANG Yuchen, SUI Yongchao, ZHOU Qin. 2022, 38(9): 837-842.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.009 Abstract ( 161 )   PDF (1716KB) ( 168 )   Objective: To measure and compare the accuracy of soft tissue contour recording by different impression methods after temporary restoration of single implant in aesthetic area. Methods: Sixteen patients were enrolled and worn implant-supported temporary crowns for at least 3 months. Digital impression and customized impression were collected. The digital indirect approach model was used as reference model (MR), and the discrepancy of gingival margin and papilla (ΔH), facial mucosa convexity (ΔDFM), and emergence profile (ΔDEP) between digital direct approach model (DS group), customized impression model (MCI group) and reference models were measured and compared. Results: In DS group, compared with MR, the height of gingival margin and papilla decreased gradually over time, ΔH was -0.21~-0.39 mm in average at 4min. The facial mucosa convexity was slightly collapsed at 1mm subgingival (-0.15±0.09)mm at 4 min, and remained stable at 2-3 mm subgingival, the emergence profile also gradually shrank with time, and the ΔDEP in the middle and apical region was significantly greater than that in the coronal region. Compared with the reference model, the height of gingival margin and papilla in MCI was decreased by 0.06-0.27 mm on average, which was similar to DS0.1. The facial mucosa was slightly bulging from the surface of MR (mean 0.03-0.09mm). Emergence profile was also narrowed, and ΔDEP in the apical region was significantly larger than that in the coronal and middle region. Compared with DS0.1, ΔDEP in the labial subgingival 1mm and 2mm of MCI was smaller, and there was no statistical significance in other sites. Conclusion: The error of digital direct approach increased gradually with the scanning time, which implies that the scanning should be completed as soon as possible. There are also errors in the customized impression transfer of peri-implant soft tissue contour. Compared with immediate scanning after removal of IR, the accuracy of recording gingival margin and papilla is similar, but the error of emergence profile is smaller. References | Related Articles | Metrics

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Effect of Short Implants on Implant Displacement, Bone Stress, and Strain Based on Biomechanical Properties. DUAN Yonghua, MEI Jian, PAN Liang, LIU Mengshi, GUO Meiling. 2022, 38(9): 843-847.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.010 Abstract ( 142 )   PDF (1446KB) ( 154 )   Objective: To explore the effects of short implants on the displacement of implants and the stress and strain of bone tissue under insufficient bone mass in maxillary posterior region based on biomechanical analysis. Methods: A prospective trial was used. A total of 65 patients with missing maxillary posterior teeth who were admitted to our hospital from January 2016 to January 2021 were included as the research subjects. They were divided into research group (n=35) and control group (n=30) according to the bone mass at their implantation sites. Short implants were used for patients with mild osteopenia in the study group, while conventional implants were used for patients with adequate bone mass in the control group. The success rate, retention rate, implant displacement, bone resorption at the neck edge, and bone tissue stress and strain of the two implants in the two groups were compared five years later, and the incidence of complications after restoration was calculated. Results: The success rate and retention rate of implants in the study group were lower than those in the control group (P>0.05). There was no significant difference in the results of re-examination of bone resorption at the neck edge between two groups at different follow-up stages (P>0.05). The maximum displacement of the implant and the maximum stress of the cortical bone in the short implant model were lower than those in the long implant model, and the maximum stress of the cancellous bone was higher than that in the long implant model. The maximum displacement value of the implant, the maximum strain value of the cancellous bone, and the maximum stress value of the cortical bone will be decreased with the increase of the reduction ratio of the crown. The crowns of the patients in the two groups had no loose, collapse porcelain, and fall off during the follow-up period. There were no complications such as swelling of the implant neck membrane and no bone destruction around the implant. Conclusion: Short implants have the same curative effect as conventional implants, but short implants can reduce the difficulty of implant surgery in the posterior maxillary area to a certain extent. From the biomechanical point of view, proper reduction of crown diameter can promote the reduction of implant displacement and the change of stress value of bone tissue. References | Related Articles | Metrics

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Clinical Trial of Small Intestinal Submucosa Absorbable Bio-films in Reconstruction of Alveolar Bone and/or Soft Tissues. JU Jia, LIU Yuhua, ZHAO Jizhi, ZHAO Jihong, LI Hongwei, WANG Baoyan, WANG Hu, ZHANG Huan, FENG Bin, HU Kaijin 2022, 38(9): 848-853.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.011 Abstract ( 230 )   PDF (1226KB) ( 368 )   Objective: To evaluate the efficacy and safety of small intestinal submucosa (SIS) absorbable biofilms in reconstructing alveolar bone and/or soft tissue. Methods: Randomized, single-bind, parallel-control, multicenter, non-inferiority trial design was used. The main measures were the changes of the maximum length, height, and width in alveolar bone 0 and 180 days after operation. Secondary measures included changes in alveolar bone hyperplasia and resorption, changes in alveolar bone matrix marginal line, damage of biofilm, surgical incision healing, rejection reaction, and post-filling symptoms. The safety of SIS absorbable biofilms was evaluated by frequency and severity of adverse events. Results: A total of 280 cases were included in this study. Two hundred and seventy-two cases completed the trial and the abscission rate was 2.86% (8 cases). The imaging effective rate of FAS (PPS) after 180 days was 83.57% (91.34%) in the experimental group and 81.43% (92.62%) in the control group, and 95%CI was 2.14% (-6.75%, 11.04%) in FAS and -1.28% (-8.03%, 5.46%) in PPS (P>0.05). The changes of alveolar bone growth and resorption, alveolar bone matrix marginal line, experimental membrane damage 12 days after surgery, clinical incision healing, rejection reaction, and filling status of each visiting point had no significant differences between two groups (P>0.05). The incidence of adverse events and serious adverse events during the treatment had no significant difference (P>0.05). Conclusion: SIS absorbable biofilms were non-inferior to Bio-Gide absorbable biofilms in reconstructing alveolar bone and/or soft tissue. References | Related Articles | Metrics

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Analysis of Related Factors for Fractures After BSSRO in Patients with Osseous Mandibular Deviation. CAO Yongqing, LI Fangfang, XU Yong, HUANG Zhen, WANG Yujiang. 2022, 38(9): 854-858.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.012 Abstract ( 144 )   PDF (1604KB) ( 159 )   Objective: To investigate the related factors of jaw fractures in patients with osseous mandibular deviation after orthognathic surgery. Methods: Twenty-three patients with bony mandibular deviation who underwent bilateral sagittal split osteotomy and retraction (BSSRO) were selected. The postoperative healing status of the patients was reviewed, and the relationship between the direction of mandibular deviation, wound infection, the way of medial ramus dehiscence, and the occurrence of jaw fractures after BSSRO was analyzed. Results: There had 3 mandibular fractures, 7 infections, 32 types of bone dehiscence in type Ⅰ and 14 in type Ⅱ, and 10 cases of left deviation and 13 cases of right deviation. There were significant differences between wound infection and medial dehiscence of the ascending ramus and fractures after BSSRO. There was a certain correlation between wound infection and postoperative fractures. Type Ⅱ bone dehiscence was more prone to fracture than type Ⅰ bone dehiscence, while there was no statistical significance between the direction of mandibular deviation and jaw fracture after BSSRO. Conclusion: The mandibular fracture after BSSRO in patients with mandibular deviation is related to the dehiscence pattern of the medial ascending ramus and wound infection. The jaw structure should be fully analyzed before the operation. The comprehensive analysis of the dehiscence pattern of the mandibular ascending ramus and the prevention of postoperative wound infection are of great significance to the prevention and treatment of postoperative fractures. References | Related Articles | Metrics

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Study on Application of Two Microdynamic Systems in Extraction of Maxillary Mid-high Mesial Impacted Wisdom Teeth. ZHOU Lei, WANG Chuanjiang 2022, 38(9): 859-862.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.013 Abstract ( 203 )   PDF (1597KB) ( 256 )   Objective: To compare the application of high-speed electric contra-angle handpiece and ultrasonic osteotome with contra-angle turbine handpiece in the extraction of maxillary medium-high mesial obstructive wisdom teeth. Methods: Forty cases of maxillary medium-high mesial obstructive wisdom teeth were randomly divided into 2 groups and extracted with high-speed electric contra-angle handpiece and ultrasonic osteotome with contra-angle turbine handpiece, respectively. The extraction time and postoperative swelling, pain, mouth opening restriction, and orofacial injury were compared between two groups. Results: The operative time of electric contra-angle handpiece group was shorter than that of ultrasonic osteotome with contra-angle turbine group, and the postoperative swelling, pain, and degree of mouth opening restriction had no significant difference between two groups. Conclusion: Electric contra-angle handpieces are efficient and have little postoperative reaction when extracting maxillary mid-high mesial obstructive wisdom teeth, which can be recommended clinically. References | Related Articles | Metrics

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Application of Computer Assisted Navigation System in Treatment of Midfacial Fracture LI Kaiyue, SU Shiheng, TAO Yuan, XUE Haowei 2022, 38(9): 863-867.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.014 Abstract ( 142 )   PDF (1738KB) ( 187 )   Objective: To evaluate the effect of computer-assisted navigation system in the treatment of midfacial fracture. Methods: Twenty-eight cases of midfacial fracture from January 2019 to December 2021 were divided into two groups, in which one group (14 cases) was used AccuNavi-A computer-assisted navigation system and another group (14 cases) was used conventional surgery. Preoperative and postoperative maxillofacial CT data were imported into software to measure the postoperative marker coordinates and then analyzed. Results: The computer-assisted navigation system was more accurate than traditional surgery. Conclusion: For midfacial fractures, surgery guided by computer-assisted navigation system has better effect than that treated with traditional way. References | Related Articles | Metrics

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Application of "Simplified" Superficial Circumflex Iliac Artery Perforator Flap in Reconstruction of Defect after Radical Surgery of Tongue Cancer. HUANG Haohao, CHEN Xin 2022, 38(9): 868-871.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.015 Abstract ( 159 )   PDF (1426KB) ( 158 )   Objective: To explore the feasibility and therapeutic effect of "simplified" superficial circumflex iliac artery perforator (SCIAP) flap in reconstruction of defect after radical surgery of tongue cancer. Methods: The "simplified" SCIAP flap, which gave up the deep branch of SCIA and dissected superficial branch as pedicle, was applied to reconstruct the defect after radical surgery of tongue cancer in 6 patients. Patients were followed up for 3-6 months to finish the evaluation of repair effect. Results: Superficial branch of SCIA were found in all 6 patients. The average area of dissected flaps was 41 (24-54) cm2, and the average length of pedicle was 6.5 (6.0-7.5) cm. The average diameter of superficial branch was 0.9 (0.5-1.2) mm, while the average diameter of superficial iliac circumflex vein was 1.6 (1.0-2.0) mm. Five patients achieved successful outcome with satisfying form of flap and good recovery of function such as phonetic and eating function. One patient ended with failure because of vascular crisis and replaced with left radial forearm free flap. Then, the skin paddle of SCIAP flap was fixed into full-thickness skin graft to repair the defect in forearm area. Wounds in iliac region were sutured directly and achieved primary healing with a hidden scar in all patients. Conclusion: "Simplified" SCIAP flap is easy to dissect, and it's satisfying in reconstruction of defect after radical surgery of tongue cancer with a hidden scar of iliac region and low donor-site morbidity. It is worth to be popularized clinically. References | Related Articles | Metrics

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Effects of Porphyromonas Gingivalis GroEL on Human Umbilical Vein Endothelial Cells. YAN Rui, GUO Kaili, CAO Fengdi, ZHANG Jun, MA Zhe 2022, 38(9): 872-876.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.016 Abstract ( 143 )   PDF (1794KB) ( 152 )   Objective: To investigate the effects of GroEL, a metabolite of Porphyromonas gingivalis(P.g) , on the proliferation viability, apoptosis, and inflammation response of human umbilical vein endothelial cell (HUVEC) in vitro. Methods: The HUVEC were stimulated with different concentrations of P.g GroEL (2, 4, 6, 8, 10 μg/mL) for 24 h to observe the morphologic changes. The proliferation viability of HUVEC was detected by CCK-8. Apoptosis rate of HUVEC was detected by flow cytometry. The expressions of interleukin-6 (IL-6), interleukin-8 (IL-8), intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin were detected by RT-qPCR and ELISA, respectively. Results: P.g GroEL significantly decreased HUVEC viability, and apoptosis rate was increased at 24 h (P<0.05). The inhibitory effect of P.g GroEL and apoptosis rate was more obvious as the concentration increased. P.g GroEL also promoted the expression of IL-6, IL-8, ICAM-1, VCAM-1, and E-selectin (P<0.05). Conclusion: P.g GroEL may play an important role in the development of atherosclerosis promoted by periodontitis. References | Related Articles | Metrics

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A Study on Activation of Autophagy in Human Periodontal Ligament Cells by Reactive Oxygen Species in Starvation Environment. HE Haiyan, YU Jinghong, WU Yujie, Zhang Min, XU Xiaomei 2022, 38(9): 877-881.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.017 Abstract ( 128 )   PDF (2249KB) ( 152 )   Objective: To study the changes of autophagy levels of human periodontal ligament cells (hPDLCs) under starvation conditions, and to explore the role of reactive oxygen species (ROS) in the process of autophagy. Methods: hPDLCs were isolated and cultured. EBSS was applied to simulate a nutrient-deficient environment. Transmission electron microscopy was used to observe the production of autophagosomes to evaluate the autophagy level in hPDLCs. In order to explore the potential regulatory mechanism of autophagy activation under starvation conditions, hPDLCs were pretreated with antioxidants N-acetylcysteine (NAC) to inhibit the generation of ROS. DCFH-DA staining was used to detect the level of ROS, and the intensity of autophagy were monitored by RT-qPCR and Western blot which measure the expression of autophagy-related proteins LC3-Ⅱ, Beclin-1, and p62. Results: After EBSS starvation, the autophagy level increased. In addition, NAC partially reversed the autophagy levels in starved hPDLCs by inhibiting ROS production. Conclusion: ROS act as a signal molecule to mediate autophagy. Starvation activates autophagy in hPDLCs by inducing ROS generation which protects cells from nutritional deficiency. References | Related Articles | Metrics

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In Vitro Study on Effect of Three Methods of Debridement on Periodontitis Root Surface XIA Jiaojiao, ZHANG Ye, LI Houxuan 2022, 38(9): 882-886.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.018 Abstract ( 173 )   PDF (1848KB) ( 265 )   Objective: To assess the damage of three instruments to the root surface of periodontitis, and to provide reference for the reasonable selection in the treatment of periodontal maintenance. Methods: Forty-three teeth with severe periodontitis were randomly demarcated into 66 regions of 4 mm×4 mm. After subgingival scaling, the remaining areas were randomly divided into ultrasonic group, manual group, and sandblasting group. The root surface debridement was completed several times. The root surface roughness values (Ra) before treatment, after the first treatment, after the 20th treatment, after the 50th treatment, and after the 100th treatment were recorded for each group. The surface of root was observed under scanning electron microscope (SEM). Results: With the increase of debridement times, the root surface in all three groups gradually became smooth, but the roughness of the root surface in the manual group changed the most. Ra was significantly improved after the first treatment (P<0.05). The root surface polishing effect was the best in the sandblasting group, and Ra was stable after the 20th treatment. SEM observation demonstrated that the manual group had the best debridement effect on the root surface, but the damage to the root surface was the most serious, followed by ultrasound, and the sandblasting group had the least damage, and the best retention effect to the root surface cementum. Conclusion: Subgingival sandblasting caused the least damage to root surface while polishing the root surface, followed by ultrasonic, and then the manual instrument. Sand blasting is recommended for cleaning plaque biofilms during maintenance and treatment to preserve root tissue as much as possible. References | Related Articles | Metrics

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Effects of Low Intensity Laser Combined with FM-SRP on Levels of TGF-β1, t-AP, and PAI-1 in Gingival Crevicular Fluid of Patients with Chronic Periodontitis YAO Lingling, HUANG Manying, XIONG Jiwen 2022, 38(9): 887-891.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.019 Abstract ( 130 )   PDF (853KB) ( 221 )   Objective: To explore the effects of low intensity laser combined with FM-SRP on the levels of TGF-β1, t-AP, and PAI-1 in gingival crevicular fluid of patients with chronic periodontitis. Methods: In this prospective study, 28 patients with chronic periodontitis admitted to our hospital from October 2019 to August 2021 were selected and divided into observation group and control group by random number table method. Patients in the control group received FM-SRP treatment, and patients in the observation group received FM-SRP treatment supplemented by low-intensity laser. Pain score, periodontal clinical indicators, inflammatory factors, vascular endothelial function, GCF transforming growth factor, t-AP, PAI-1, and adverse reactions were compared between two groups. Results: The pain score in the observation group was significantly lower than that of control group at 3d after treatment. After treatment, gingival bleeding index, probing depth, clinical attachment loss, and plaque index in the observation group, were significantly lower than those in the control group. Interleukin-8, matrix metalloproteinase-7, and high mobility group protein B1 in the observation group were significantly lower than those in the control group. The FMD and NMD in the observation group were significantly higher than those in the control group ingival crevice fluid transforming growth factor β1 and t-AP in the observation group were significantly higher than those in the control group, and the PAI-1 of gingival crevicular fluid in the observation group was significantly lower than that in the control group. Conclusion: Low intensity laser combined with FM-SRP in the treatment of chronic periodontitis can effectively relieve pain, eliminate inflammation, improve vascular endothelial function, improve periodontal status indicators, and may be associated with the reduction of gingival crevicular fluid transforming growth factor and t-AP and improvement of PAI-1 level, which is safe and worthy of clinical promotion. References | Related Articles | Metrics

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Retrospective Survey and Prospect on Research of Dental Diseases at the Qing Court ZHANG Jingqiu, ZHU Mengdi, WANG Yifei, WANG Jiabo, WANG Songling, ZHOU Jian 2022, 38(9): 892-898.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.020 Abstract ( 198 )   PDF (1311KB) ( 306 )   Research of dental diseases at the Qing Court originated during Republic of China, when the related research achievements focused on literature and relics sorting and publishing. In 1925 the Committee to Deal with the Concerns of the Deposed Imperial Family sorted and counted items at the Court and published the Publication of the Report of Palace Museum Inventory, where it can be seen that the period dental disease treatment instruments at the court were stored at the east room of Kunning Gate, classified to modern dentistry instruments; false teeth and dentures stored at pharmacy of Kunning Palace and other palaces; teeth fumigating silver devices stored at the Hall of Mental Cultivation; false teeth and dentures also found at Shoukang Palace. Since later 1950s, a large amount of literature at the Qing Court has been sorted, including documents about dental diseases and varied historical relics for dental diseases treatments been made public. At present research of Dental Diseases at the Qing Court is promising, for that it is helpful for deeper research of royal medicine, that it provides valuable research models of medical existence mode and relation to its environment under traditional Chinese and western medicine coexisting and that it provides literature and historical documents for conceiving and composing history of Chinese Stomatology. References | Related Articles | Metrics

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Minimally Invasive Extraction of Anterior Part of Left Maxilla with Combined Odontoma and Impacted Teeth: A Case Report. SU Liwen, WU Yang 2022, 38(9): 899-901.  DOI: 10.13701/j.cnki.kqyxyj.2022.09.021 Abstract ( 270 )   PDF (2665KB) ( 496 )   It is rare that odontoma, embedded supernumerary teeth, and permanent impacted teeth occur simultaneously in maxillary anterior teeth area. In this paper, we present a case of minimally invasive extraction of combined odontoma, impacted maxillary canine, and supernumerary tooth in the left maxillary anterior teeth area and briefly discusses its incidence, treatment principle, difficulty, and risk of operation. References | Related Articles | Metrics