Journal of Oral Science Research ›› 2015, Vol. 31 ›› Issue (10): 1004-1007.

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Effect of Dental Implant Surgery on Levels of Serum BGP and AKP, Saliva Calcium and Phosphorus in Patients with Postmenopausal Osteoporosis

YANG Lei, ZHANG Li, ZHANG Yong, DAN Jin-xue   

  1. Handan Stomatological Hospital, Handan 056001, China
  • Received:2015-03-09 Online:2015-10-28 Published:2016-05-04

Abstract: Objective: To investigate the effect of dental implant surgery on levels of serum bone gla protein (BGP), alkline phosphatase (AKP), saliva calcium, and phosphorus in patients with postmenopausal osteoporosis. Methods: Seventy-four patients were grouped according to gender and their bone quality, menopausal status. Their saliva and serum were collected at different time points. Results: The levels of estrone, estradiol, and testosterone in Group A and B were significantly lower than those of Group C (P<0.05). The levels of BGP and AKP in Group A and B were higher those of Control group (P<0.05). Dental implant surgery significantly enhanced the BGP levels. Additionally, the saliva calcium and phosphorus had the same tendency as BGP. Conclusion: Lower estrogen level in postmenopausal patients resulted in osteoporosis, and led to the increase of BGP and AKP in serum, and calcium and phosphorus in saliva compared to the control group. After dental implant surgery, the level of calcium in saliva was positively associated with the level of BGP.

Key words: Postmenopausal osteoporosis, BGP, Calcium, Dental implant surgery

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