Journal of Oral Science Research ›› 2022, Vol. 38 ›› Issue (3): 212-215.DOI: 10.13701/j.cnki.kqyxyj.2022.03.002

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Research Progress of Three-dimensional Graphene and Its Derivatives in Osteogenesis of Dental Stem Cells

YE Qing, LI Jiyao*   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-12-16 Online:2022-03-28 Published:2022-03-25

Abstract: Graphene is a novel material with broad applications in many fields. Its research in biomedical field is increasing in recent years. Three-dimensional graphene refers to the two-dimensional graphene assembly with three-dimensional structure. The three-dimensional structure shows better porosity and larger surface area of graphene, which improves the adhesion and growth of cells, making it capable of inducing bone formation of mesenchymal stem cells. Based on the physical and chemical properties and biocompatibility of three-dimensional graphene, this review summarizes the researches on three-dimensional graphene and its derivatives in inducing osteogenesis of dental stem cells, with hope to provide reference for the osteogenesis application of graphene in dental research.

Key words: graphene, dental stem cells, bone tissue engineering