Journal of Oral Science Research ›› 2019, Vol. 35 ›› Issue (10): 919-921.DOI: 10.13701/j.cnki.kqyxyj.2019.10.002

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Research Progress in Osteogenic Differentiation Mechanism of Adipose-derived Stem Cells.

LIU Xiangdong, SONG Yingliang*   

  1. State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Implant Dentistry, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China.
  • Received:2018-11-13 Online:2019-10-28 Published:2019-10-22

Abstract: Increasing implant osseointegration, especially for diabetic patients, is one of the problems that every oral implant doctor is facing. Adipose derived stem cells (ASCs) provide new ideas for solving above problems. However,its osteogenesis needs improving. This article mainly summarizes the effective methods of osteogenic differentiation of ASCs and its specific mechanism. The focus is on microRNA, Semaphorin3A and these possible mechanisms. Lastly, we look forward to future research findings.

Key words: adipose-derived stem cells, microRNA, Semaphorin3A