Journal of Oral Science Research ›› 2024, Vol. 40 ›› Issue (4): 287-292.DOI: 10.13701/j.cnki.kqyxyj.2024.04.002

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Advancement of Dental Stem Cells-derived Exosomes in Periodontal Tissue Regeneration

SUN Yifan, HONG Lihua*   

  1. Department of Endodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2023-07-24 Published:2024-04-22

Abstract: Periodontitis is a common oral disease affecting the health and quality of life. Achieving satisfactory regeneration of periodontal tissue structure and function to preserve more teeth is the goal of treatment. Exosomes are nano vesicles containing a variety of biologically active substances, which can participate in intercellular information exchange and material transfer upon cellular uptake. The unique tissue specificity of dental stem cells makes the exosomes derived from them one of the hot spots in periodontal tissue regeneration. This paper reviews the latest progress of exosomes derived from dental stem cells in periodontal tissue regeneration, with a view to provide new ideas for periodontitis-related research.

Key words: exosome, mesenchymal stem cell, periodontitis tissue regeneration