Abstract: A cases of primary gingival B cell lymphoma is reported in this paper. The patientwas male, 28-years-old with the left maxillary gingival painless gradually proliferated for 1 month. Special examination showed a 2cm×1.5cm×1cm tumor located in 23, 24 and 25 of the buccal gingiva. Image tests revealed a broadened periodontal membrane. The buccal bone was low density image with not clear boundary. Histopathologically,abnormallymphocyteswere seen arranged in disperse. Immunohistochemicalexamination demonstrated: CD20(-),CD2(-),CD10(+),CD138(+),CD79a(+),LCA(+), and Ki-67 around 80%(+).The diagnosis was primary gingival B cell lymphoma.

Key words: B cell lymphoma, Gingival, Immunie