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Application of Multi types of Digital Images Matching and 3D Printing Technology in the Treatment of Condylar Tumor MA Wen, WEI Yi, LU Lin, FU Shuai, ZHANG Changbin, CUI Qingying, PENG Canbang, WANG Lidong, XU Yanhua, LI Ming Journal of Oral Science Research    2021, 37 (1): 81-86.   DOI: 10.13701/j.cnki.kqyxyj.2021.01.018 Abstract （177）      PDF （3405KB）（951）       Objective: To investigate the clinical significance of multiple types of digital images matching and 3D printing technology in the treatment of condylar tumors. Methods: According to patient's spiral CT data, CTA data of blood vessels, 3D scanning data of teeth, the maxillary, mandible, soft tissue and condylar tumors with surrounding important anatomic structures were reconstructed using Mimics 21.0(Materialise, Belgium). Then, matching the 3D scanning of teeth with bones data from spiral CT, matching the soft tissue with bones. Finally, in the same coordinate system, the three-dimensional model of the maxillary and mandible complex with tooth information, condylar tumors and surrounding blood vessels were obtained. Designing and 3D printing splint was assisted operation. Results: All 6 patients were underwent the operation successfully with the wounds healed at the same time. The occlusal relationship of all patients were well. The postoperative CBCT showed that complete resection of tumors and no signs of recurrence were found in long term follow-up. Conclusion: Multi types digital image matching and 3D printing splint could accurately reconstruct the important anatomic structures such as condylar tumors and peripheral blood vessels, so as to fully understand the operation area before operation. At the same time, personalized 3D splint was designed to create space for operation and reduce the damage of surrounding tissues. This method could be used as an auxiliary way to treat patients with condylar tumors. Reference | Related Articles | Metrics

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Progress in Pain Management after Extraction of Impacted Mandibular Third Molars ZHOU Shizheng, ZOU Haixiao Journal of Oral Science Research    2024, 40 (2): 103-107.   DOI: 10.13701/j.cnki.kqyxyj.2024.02.002 Abstract （156）      PDF （806KB）（446）       In order to relieve the postoperative pain and improve the quality of life, relevant experts recommend systematic management of tooth extraction pain, so as to improve the prognosis of patients. This review aimed to introduce the mechanism and types of pain and the intervention of pain after mandibular third molars extraction, with a view to provide guidance for the clinical management of pain in mandibular impacted third molars extraction. Reference | Related Articles | Metrics

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Research Progress on Mandible-first Sequencing in Bimaxillary Orthognathic Surgery LIU Yao, WAN Qilong Journal of Oral Science Research    2021, 37 (6): 501-504.   DOI: 10.13701/j.cnki.kqyxyj.2021.06.005 Abstract （327）      PDF （842KB）（630）       Two common sequences of bimaxillary orthognathic surgery are maxillary-first and mandible-first. During maxillary-first sequence, maxilla is repositioned and stabilized firstly, then using the stable maxilla to reposition the mandible. On the contrary, during mandible-first sequence, the mandible is firstly repositioned and stabilized, followed by repositioning the maxilla. Although there were significant advantages to support the using of mandible-first sequence, controversial still remains. The goal of this article is to review the application and research progress of mandible-first to assist surgeons in determining the sequence of bimaxillary orthognathic surgery. Reference | Related Articles | Metrics

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Research Progress on Structure and Mechanical Properties of Dental Enamel LIU Jitao, CHEN Qinghua Journal of Oral Science Research    2020, 36 (3): 213-215.   DOI: 10.13701/j.cnki.kqyxyj.2020.03.006 Abstract （561）      PDF （767KB）（998）       The hierarchical structure of enamel composes the basis of its mechanical properties such as high hardness and high toughness. Understanding the mechanical properties of microstructures in enamel is helpful to the development of biomimetic restoration materials and the remineralization of dental enamel in clinical. In this review, the structure and mechanical properties of enamel were systematically reviewed in terms of its hierarchical structure and toughening mechanism brought by organic components, dentin-enamel junction, and hydration. The gradual hierarchical structure of enamel and the high contact area of dentin-enamel junction lead to the gradient distribution of mechanical properties, making enamel both rigid and toughness. Organic components such as a small amount of viscoelastic proteins and their hydration play an important role in energy dissipation, preventing crack propagation in the enamel and maintaining the structural integrity of the teeth. The investigations in the precise hierarchical structure of dental enamel and the complex synergistic toughening mechanism between inorganic and organic components provide new ideas for the development of biomimetic nanocomposites. Reference | Related Articles | Metrics

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Research Progress on Central Regulation Mechanism of Dental Pulp Inflammatory Pain WANG Yanqi, SUN Shukai Journal of Oral Science Research    2023, 39 (1): 15-19.   DOI: 10.13701/j.cnki.kqyxyj.2023.01.003 Abstract （266）      PDF （873KB）（507）       Pain is the main reason why children refuse to cooperate with treatment when seeing a doctor. How to reduce pain, avoid dental anxiety, and improve the rate of cooperation in diagnosis and treatment is a great challenge for pediatric dentists. Pulpitis is one of the most common oral diseases that cause toothache. The conduction pathway of toothache is that C fiber and Aδ fiber in pulp nerve transmit stimulation to trigeminal ganglion (TG), and further to the central nervous system. Anatomical studies have confirmed that trigeminal spinal subnucleus caudalis (Ⅴc), also known as the medullary dorsal horn (MDH), receives projections from primary afferent fibers of dental pulp and plays an important role in pain transmission. This paper reviews the relevant literature on dental pulp inflammatory pain in recent years, and summarizes the role of neurons and microglia in pain regulation in Ⅴc, which aims to look for more therapeutic targets for dental pulp inflammatory pain. Reference | Related Articles | Metrics

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Research Progress on Antibacterial Mechanism and Bone Promoting Efficacy of Carbon Quantum Dots YAO Minhui, MA Qian Journal of Oral Science Research    2024, 40 (7): 573-577.   DOI: 10.13701/j.cnki.kqyxyj.2024.07.001 Abstract （108）      PDF （805KB）（298）       Carbon quantum dots (CQDs) is a novel biofluorescent carbon nanomaterial which could be easily synthesized and modified. It has excellent properties such as good biocompatibility, chemical stability, and photoelectric properties. Moreover, CQDs shows great potential in the field of antibacterial and bone regeneration. In this study, we reviewed the common characteristics of CQDs, especially its antibacterial effects, antibacterial mechanism, and properties of promoting bone differentiation. Meanwhile, we investigate its potential role as a treatment agent for oral infectious maxillofacial bone defects. Reference | Related Articles | Metrics

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New Progress in the Treatment of Adenoid and Tonsil Hypertrophy in Children ZHAO Jiaqi, SHAN Lihua Journal of Oral Science Research    2021, 37 (8): 693-695.   DOI: 10.13701/j.cnki.kqyxyj.2021.08.005 Abstract （397）      PDF （787KB）（981）       Chronic upper airway obstruction or dysfunction in children can cause open mouth breathing, produce adenoid face, and in severe cases lead to obstructive sleep apnea hypopnea syndrome (OASHS), which can seriously affect the children's growth, development, and cognition. Adenoid and tonsil hypertrophy are the main cause of upper airway obstruction in children. This paper discusses the effects of upper airway obstruction on maxillofacial and systemic growth in children, the selection of different treatment methods, and the latest research progress. Children with upper airway obstruction require multidisciplinary cooperative sequential therapy. Reference | Related Articles | Metrics

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Introduction and Assessment of Dental Pulp Vitality Test YANG Jinghui, YUAN Guohua Journal of Oral Science Research    2021, 37 (3): 195-199.   DOI: 10.13701/j.cnki.kqyxyj.2021.03.003 Abstract （526）      PDF （802KB）（1254）       Pulp vitality is the basis of the diagnosis and treatment of dental pulp disease. Cold pulp test, hot pulp test, and electric pulp test are widely applied to clinical diagnosis, and they are collectively known as pulp sensitivity test. But at present, stomatologists find that there are many deficiencies in sensitivity test, and in some cases such as young permanent teeth show high misdiagnosis rate. In order to improve the diagnostic accuracy, the dental pulp blood flow test is proposed, greatly reducing the rate of misdiagnosis. However, it is not widely used in clinic. In addition, magnetic resonance imaging and quantitative test of biomarkers are also considered to judge the pulp vitality in theoretical aspect. This paper briefly introduces several methods to judge the pulp vitality and the advantages and disadvantages of them. Reference | Related Articles | Metrics

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The S3 Level Clinical Diagnosis and Practice Guideline of Stage Ⅳ Severe Periodontitis Based on 2018 EFP/AAP Classification CAO Zhengguo, GAO Ya, ZENG Yu Journal of Oral Science Research    2023, 39 (11): 943-951.   DOI: 10.13701/j.cnki.kqyxyj.2023.11.001 Abstract （209）      PDF （8311KB）（1094）       The early symptoms of periodontitis are not obvious, while it always accompanied by severe alveolar ridge defects, tooth drifting, flaring, and even tooth loss in advanced stage. It leads to a heavy burden on the country, society, and patients themselves with high prevalence. In 2018, consensus reports on the Classification of Periodontal and Peri-implant Diseases and Conditions were published by the American Academy of Periodontology (AAP) and European Federation of Periodontology (EFP), which divided periodontitis into four stages and three grades. Subsequently, the EFP has published S3-level clinical guidelines for the treatment of stage Ⅰ-Ⅲ and stage Ⅳ periodontitis. This article will discuss the clinical diagnosis and treatment practice of severe periodontitis based on the 2018 Classification with a case of periodontitis (stage Ⅳ, grade C). Reference | Related Articles | Metrics

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Research Progress on Mechanism of Macrophages Affecting Bone Formation NIE Zhangling, BAO Chongyun Journal of Oral Science Research    2021, 37 (11): 966-969.   DOI: 10.13701/j.cnki.kqyxyj.2021.11.002 Abstract （640）      PDF （827KB）（649）       Macrophages play a key role in bone formation, and their specific performance is regulated by multiple complex biological mechanisms. Specifically, certain signaling molecules secreted by macrophages, such as oncostatin M (OSM), prostaglandin E2 (PGE2), bone morphogenetic protein-2 (BMP-2), and tumor necrosis factor-α (TNF-α), have a key role in osteogenesis. In addition, polarized subtypes of macrophages also play a regulatory role at different stages of osteogenesis. This article reviews the research progress of the related mechanisms of macrophages influencing bone formation in recent years. Reference | Related Articles | Metrics

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Research Progress on Biomimetic Mineralization of Dentin HE Ting, ZHANG Linglin Journal of Oral Science Research    2021, 37 (10): 886-889.   DOI: 10.13701/j.cnki.kqyxyj.2021.10.005 Abstract （369）      PDF （792KB）（526）       Biomimetic mineralization of dentin is the focus of both oral medicine and biomaterial science. Biomimetic materials obtained by biomimetic mineralization, which are similar to natural dentin in terms of composition, structure, and function, are ideal materials for dentin repairg. In this paper, we summarize the research progress on biomimetic mineralization of dentin. Reference | Related Articles | Metrics

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Micro-CT Analysis of Osseointegration of Cortex-like Titania Implant Coatings with Micro-arc Oxidation. ZHOU Hong-zhi, LI Ya-da, LIU Huan, LIU Lin, WANG Wei-qiang, MA Guo-wu, QI Min Journal of Oral Science Research    2016, 32 (7): 676-680.   DOI: 10.13701/j.cnki.kqyxyj.2016.07.003 Abstract （281）      PDF （1494KB）（978）       Objective: To assess the osseointegration of porous titania (TiO2) coating with a novel cortex-like morphology by micro-CT. Methods: Cortex-like morphology Ti surface was produced by MAO, and SLA surface was used as control.The surface features were evaluated by scanning electron microscope (SEM) and contact Angle. Thirty-six threaded implants were placed in the femoral condyles of 18 male New Zealand White rabbits. Trabecular bone morphology parameters were analyzed after implantation 4 weeks and 8 weeks by Micro-CT. Results: Morphology microstructure of MAO cortex-like was composed of microscale and nanoscale structure, with better wettability and contact Angle (6.9±1.14)°. Along with the time of bone healing, the BV/TV, Tb. N, Tb. Th and Conn. Dn were increased, while SMI and Tb. Sp were decreased. At 4th week, statistical significances were detected in BV/TV and SMI ( P<0.05). At 8th week, statistical significances were detected in BV/TV, Tb. N, Tb. Sp and Conn.Dn ( P<0.05). Cortex-like morphology exhibited more continuous bone apposition. Conclusion: The cortex-like morphology of titanium with microscale and nanoscale topologic structure can improve the osseointegration of Ti implant and has good biocompatibility. Reference | Related Articles | Metrics

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Relationship between Ala-tragus Line and Occlusal Plane YANG Jiadi, LI Ning, BIAN Ce, WANG Xu Journal of Oral Science Research    2020, 36 (9): 835-838.   DOI: 10.13701/j.cnki.kqyxyj.2020.09.009 Abstract （325）      PDF （818KB）（503）       Objective: To compare the relationship of the occlusal plane and different Ala-tragal lines. Methods: 125 students (36 males and 89 females) with complete natural dentition and class I occlusal relationship were selected to place the plane gage in their mouths. After taking lateral photos with digital camera, the included angles between the occlusal plane and middle point of ala-upper point of tragus (A1-T1), middle point of ala-middle point of tragus (A1-T2), middle point of ala-lower point of tragus (A1-T3), lower point of ala-upper point of tragus (A2-T1), lower point of ala-middle point of tragus (A2-T2), lower point of ala-lower point of tragus (A2-T3) were measured. Results: There was no parallel between the occlusal plane and six kinds of Ala-tragus lines. There was a statistical difference between the two angles and 0° ( P<0.001), but the intersection angle between A1-T2 and the occlusal plane was the smallest (2.80°), and there was no statistical difference between A1-T1, A1-T2, A2-T3, and the occlusal plane ( P>0.05). Conclusion: The middle point of the ala-the middle point of the tragus, the middle point of the ala-the upper point of the tragus, and the lower point of the ala-the lower point of the tragus can be used as the marker line of the plane of location. Reference | Related Articles | Metrics

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Research Progress on Mouth Breathing and Oral Microecology in Children and Adolescents LI Mengru, WANG Xiaoqin Journal of Oral Science Research    2024, 40 (6): 479-483.   DOI: 10.13701/j.cnki.kqyxyj.2024.06.002 Abstract （85）      PDF （816KB）（165）       Mouth breathing, as a common problem in the growth and development of children and adolescents, has always been concerned by orthodontists. Long-term continuous chronic mouth breathing can cause abnormal growth of adolescents in the sagittal, horizontal and vertical directions. There will also have adverse changes in muscle function, including bite, cheek, and tongue muscle strength decline. In severe cases, systemic diseases can be induced. The accompanying 'adenoid and/or tonsil face' has attracted more and more attention from parents. With the launch of Human Microbiome Project in 2007, people began to pay attention to the correlation between oral microbiome changes and the occurrence and development of diseases. This article reviews the mouth breathing, oral microecology, and their correlation in children and adolescents. Reference | Related Articles | Metrics

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Research Progress on Role of Nerve in Repair of Damaged Dental Pulp WANG Chunmeng, ZHANG Qi Journal of Oral Science Research    2022, 38 (12): 1110-1114.   DOI: 10.13701/j.cnki.kqyxyj.2022.12.002 Abstract （257）      PDF （859KB）（515）       The defense and self-repair function of pulp is the biological basis of damaged pulp repair and vital pulp therapy. As an important part of pulp tissue, nerve may play a role as the initiating factor after pulp injury. Pulp injury not only results in the changes of nerve distribution, structure, and signal transduction, but also affects other tissues and cells through related bioactive molecules. This article summarizes and discusses the role of nerve in pulp injury repair in recent years, with aid to provide reference and theoretical guidance for clinical treatment of vital pulp therapy. Reference | Related Articles | Metrics

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Research Progress in Etiology and Pathogenesis of Hairy Tongue WU Sihua, CHEN Qianming Journal of Oral Science Research    2024, 40 (9): 757-761.   DOI: 10.13701/j.cnki.kqyxyj.2024.09.001 Abstract （71）      PDF （1748KB）（89）       Hairy tongue is a hairy lesion on the dorsal surface of the tongue that can be stained by food, tobacco, or microorganisms, resulting in a variety of colors such as white, tan, and black. Hairy tongue is a kind of benign lesions that can cause halitosis, dry mouth, aesthetic problems, so that patients’ quality of life is reduced. At present, the pathogenesis of hairy tongue has not been clarified. This review summarizes current studies on the etiology and pathogenesis of hairy tongue, which may be related to metabolic abnormality of filiform papillae, oral microbiota imbalance, immune abnormal phenomenon, and use of certain drugs. Reference | Related Articles | Metrics

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Research Progress on Relationship between Periodontitis and Oral as well as Gut Microbiota CHEN Qi, GONG Ting Journal of Oral Science Research    2023, 39 (2): 109-112.   DOI: 10.13701/j.cnki.kqyxyj.2023.02.004 Abstract （355）      PDF （776KB）（525）       The gut microbiota is the largest microbial community in the human body. Recent studies have shown that the gut microbiota is closely related to the health of the whole body. The gut dysbiosis plays an important role in obesity, heart disease, autism, diabetes, et al. Periodontitis is one of the most common oral diseases, manifested as alveolar bone loss, tooth loosening, etc. Recent studies have shown that periodontitis can affect the gut microbiota. This article discusses the effect of periodontitis on the gut microbiota, possible routes, and factors of oral microbiota to influence gut microbiota, in order to provide reference for exploring the correlation between periodontitis and gut microbiota. Reference | Related Articles | Metrics

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Research Progress on Canine Impaction WANG Han, GE Zhen-lin Journal of Oral Science Research    2018, 34 (11): 1158-1160.   DOI: 10.13701/j.cnki.kqyxyj.2018.11.003 Abstract （342）      PDF （805KB）（567）       Permanent canine impaction is considered as a common dental anomaly. The etiology remains poorly understood and the choices of treatment are various. This article reviewed the literature on canine impaction and the etiology, diagnosis, and treatment of impacted canine were discussed, hoping to provide reference for early clinical diagnosis and treatment. The etiology of canine impaction is related to hard tissue obstructions, local pathology, developmental disturbance, and genetic factors. CBCT and panoramic radiographs are essential for diagnosis. Orthodontic traction is the main treatment. Early detection of canine impaction gives the opportunity to stabilize stomatognathic system and contribute to the health of adjacent teeth. Reference | Related Articles | Metrics

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Clinical Application of Platform Switching Technology in Oral Implant ZHANG Ni, MENG Weiyan Journal of Oral Science Research    2023, 39 (12): 1037-1041.   DOI: 10.13701/j.cnki.kqyxyj.2023.12.002 Abstract （190）      PDF （804KB）（371）       Platform switching technology refers to the method that a smaller diameter abutment is connected to the implant to allow the implant-abutment combination to move inward toward the central axis of the implant in the process of implant restoration. Many case reports and clinical studies have shown that the platform switching technique reduced the marginal bone loss around implants, and played a positive role in improving peri-implant stress distribution, restoring biological width, and building healthy soft tissue morphology. This article reviews the clinical application of platform switching technology in implant restoration. Reference | Related Articles | Metrics

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Journal of Oral Science Research    2015, 31 (5): 531-532.   Abstract （157）      PDF （757KB）（642）       Reference | Related Articles | Metrics