Journal of Oral Science Research ›› 2017, Vol. 33 ›› Issue (2): 154-157.DOI: 10.13701/j.cnki.kqyxyj.2017.02.009

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Effect of TiN Nano-coating on Adhesion and Proliferation of Human Gingival Fibroblasts in Transmucosal Part of Dental Implant.

PAN Xia-wei1, LAI Ying-zhen1, CHEN Jiang2*   

  1. 1. Xiamen Medical College, Xiamen 361000, China;
    2. Department of Oral Implantology, Affiliated Stomatological Hospital of Fujian Medical University, Fuzhou 350002, China
  • Received:2016-08-06 Online:2017-02-20 Published:2017-02-22

Abstract: Objective: To investigate the effect of TiN nano-coating on adhesion and proliferation of the human gingival fibroblasts (HGF). Methods: TiN coatings were deposited by magnetron sputtering. Ti coatings were deposited as the controls. The morphology and roughness of nano-coatings, elementary composition and hydrophilia were determined. Morphology of HGF was analyzed by using SEM. Cell proliferation abilities were investigated by using CCK-8 Kit. Results: Morphology of HGF was similar between TiN coatings and the control. However, the cell proliferation ability was significantly increased in substrate with TiN nano-coating. Conclusion: TiN nano-coating can be applied in transmucosal part of dental implant to enhance the biocompatibility.

Key words: Soft tissue Implant , TiN nano-coating , Human gingival fibroblasts , Proliferation

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