Application and Prospect of Microfluidics in the Field of Periodontics

doi:10.13701/j.cnki.kqyxyj.2022.10.005

Abstract

Abstract: Microfluidics is a kind of device, which uses analytic biology and chemistry as the research object, integrates sample preparation, reaction, separation, and detection into a piece of a few square centimeters chip, forms network by micro channel, runs through the system with controllable fluid, and replaces the test of conventional biochemical laboratory. In recent years, the device has gradually become a hot research issue in the diagnosis and treatment of periodontal disease, mainly related to periodontal pathogens and protein biomarkers detection, and drug research and development of periodontal therapy. A large number of studies have shown that microfluidics plays an important role in basic research and clinical research in the field of periodontics. In addition, it has great potential to replace traditional biological laboratories and become a novel periodontal disease research method in the future. Starting from the related concepts and technologies of microfluidics, this paper reviews the application of microfluidics in the diagnosis and treatment of periodontal disease, and looks forward to its possible application directions in the periodontal field in the future, so as to provide experimental ideas and references for researchers in related fields.

Key words: microfluidics, periodontal disease, point-of-care testing, biofilm

LIU Enyan, DING Yi. Application and Prospect of Microfluidics in the Field of Periodontics[J]. Journal of Oral Science Research, 2022, 38(10): 926-929.

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